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In vitro activity of six antiviral drugs against equid alphaherpesvirus type 1 ...

Oliveira,Amanda Lovato de; Cargnelutti,Juliana Felipetto; Mortari,Ana Paula Gnocato; Flores,Eduardo Furtado; Weiblen,Rudi

ABSTRACT: Equid alphaherpesvirus type 1 (EHV-1) is distributed worldwide and is a major agent of abortion, respiratory and neurological disease in horses. No specific treatment is available for EHV-1 infection, yet the potential of antiviral therapy has been explored. In this study we investigated the in vitro activity of Acyclovir, Ganciclovir, Foscarnet, Famciclovir, Vidarabina and Cidofovir against EHV-1. Fo...

Date: 2018   |   Origin: Oasisbr

Antibodies against rabies virus in dogs with and without history of vaccination...

Fernandes,Karina Gonzalez; Martins,Mathias; Amaral,Bruna Portolan; Cargnelutti,Juliana Felipetto; Weiblen,Rudi; Flores,Eduardo Furtado

ABSTRACT: The present study investigated the frequency and magnitude of neutralizing antibodies to rabies virus (RABV) in dogs with and without historic of vaccination in Santa Maria/RS. Group A included serum samples from 440 dogs with recent historic of vaccination against rabies, obtained during the 2015 rabies vaccination campaign. Group B included 300 serum samples from dogs submitted to the Veterinary Hos...

Date: 2017   |   Origin: Oasisbr

Experimental infection of horses with Vaccinia virus

Barbosa,Claudio Henrique Gonçalves; Sant'Ana,Fabiano José Ferreira de; Cargnelutti,Juliana Felipetto; Flores,Eduardo Furtado

ABSTRACT: Vaccinia virus (VACV) is the etiologic agent of bovine vaccinia, an emerging zoonotic disease with potential health issues for dairy herds and humans. VACV may occasionally infect other species, including horses. In this sense, an outbreak of VACV disease in horses was described in Pelotas, RS, in 2008, where a co-infection with two VACV strains (named Pelotas Virus 1 [P1V] and Pelotas Virus 2 [P2V]) ...

Date: 2016   |   Origin: Oasisbr

Detection of respiratory viruses in shelter dogs maintained under varying envir...

Monteiro,Francielle Liz; Cargnelutti,Juliana Felipetto; Martins,Mathias; Anziliero,Deniz; Erhardt,Magnólia Martins; Weiblen,Rudi; Flores,Eduardo Furtado

Abstract Three dog shelters in Rio Grande do Sul were investigated for associations between the occurrence of respiratory viruses and shelter environmental conditions. Nasal secretions randomly collected during the cold season were tested via PCR, and this data collection was followed by nucleotide sequencing of the amplicons. In shelter #1 (poor sanitary and nutritional conditions, high animal density and cons...

Date: 2016   |   Origin: Oasisbr

Virus isolation in cell culture for confirmatory diagnostic of rabies in bovine...

Kanitz,Fabio Adriano; Cargnelutti,Juliana Felipetto; Weiblen,Rudi; Batista,Helena Beatriz de Carvalho Ruthner; Flores,Eduardo Furtado

ABSTRACT: This study investigated the suitability of virus isolation (VI) in mouse neuroblastoma cells (N2A) and baby hamster kidney cells (BHK-21) as a confirmatory test for diagnosis of bovine rabies. Fourty-eight brain samples from cattle suspected of rabies were initially submitted to fluorescent antibody test (FAT) and mouse inoculation test (MIT) for routine diagnostic. Subsequently, these specimens were ...

Date: 2015   |   Origin: Oasisbr

Pseudovaríola e estomatite papular em bovinos no Estado de Rondônia, Brasil

Cargnelutti,Juliana Felipetto; Santos,Bethânia Silva; Lebre,Sabrina das Neves; Sodré,Débora Naihane Alves; Silva,Rogério Mandu da; Weiblen,Rudi

Casos de doença vesicular, suspeitos de febre aftosa ou estomatite vesicular, foram acompanhados em rebanhos de cria e recria de bovinos no município de Nova Brasilândia do Oeste, região centro-sul do Estado de Rondônia, nos meses de outubro e novembro de 2012. Os casos ocorreram em 13 rebanhos próximos, sendo que amostras de nove rebanhos foram submetidas ao diagnóstico laboratorial. O surto afetou 25 do total...

Date: 2014   |   Origin: Oasisbr

Emerging animal viruses: real threats or simple bystanders?

Flores,Eduardo Furtado; Weiblen,Rudi; Cargnelutti,Juliana Felipetto; Bauermann,Fernando Viçosa; Spilki,Fernando Rosado; Mori,Enio; Franco,Ana Cláudia

The list of animal viruses has been frequently added of new members raising permanent concerns to virologists and veterinarians. The pathogenic potential and association with disease have been clearly demonstrated for some, but not for all of these emerging viruses. This review describes recent discoveries of animal viruses and their potential relevance for veterinary practice. Dogs were considered refractory t...

Date: 2013   |   Origin: Oasisbr

Guinea pigs experimentally infected with vaccinia virus replicate and shed, but...

Cargnelutti,Juliana Felipetto; Wendlant,Adriéli; Weiblen,Rudi; Flores,Eduardo Furtado

The origin of vaccinia viruses (VACV) associated with vesicular disease in cattle and humans in Southeast Brazil remains uncertain, yet the role of wild species in virus transmission has been suggested. This study investigated the susceptibility and transmission potential by guinea pigs (Cavia porcellus) - phylogenetically close to an abundant Brazilian rodent (Cavia aperea) - to two VACV strains (P1V and P2V) ...

Date: 2012   |   Origin: Oasisbr

Vacina experimental produzida em cultivo celular confere proteção parcial contr...

Schmidt,Candice; Cargnelutti,Juliana Felipetto; Martins,Mathias; Weiblen,Rudi; Flores,Eduardo Furtado

O ectima contagioso (também conhecido como orf), é uma doença debilitante de ovinos e caprinos causada pelo vírus do orf (ORFV). A vacinação tem sido usada com relativo sucesso no controle da doença. No entanto, as vacinas atuais contêm amostras virulentas do agente, são produzidas por escarificação cutânea de animais, e apresentam eficácia questionável. Assim, o presente trabalho teve como objetivo produzir e ...

Date: 2012   |   Origin: Oasisbr

Pesquisa de anticorpos anti-Neospora spp. e anti-herpersvírus equino em cavalos...

Sangioni,Luís Antonio; Botton,Sônia de Avila; Cargnelutti,Juliana Felipetto; Cadore,Gustavo Cauduro; Cezar,Alfredo Skrebsky; Weiblen,Rudi

O presente estudo teve como objetivo investigar a ocorrência de anticorpos contra Neospora spp. e o herpesvírus equino (EHV) em soros de cavalos de tração de Santa Maria, RS, Brasil. Os soros sanguineos provenientes de 91 animais do projeto de extensão da Universidade Federal de Santa Maria "Programa de Ação Social Amigos do Carroceiro" (PASAC) foram colhidos no período de março de 2006 a maio de 2008 e submeti...

Date: 2011   |   Origin: Oasisbr

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