9 documents found, page 1 of 1
Biomimetic bright optotheranostics for metastasis monitoring and multimodal ima...
Prasad, Rajendra; Peng, Berney; Mendes, Bárbara B.; Kilian, Hailey I.; Gorain, Mahadeo; Zhang, Huijuan; Kundu, Gopal Chandra; Xia, JunFunding Information: R.P. would like to thank the Director and the School of Biochemical Engineering, Indian Institute of Technology (BHU), Varanasi for the support during preparation of this manuscript. R.P. also thanks the support of Tufts University , J.C. and B.B.M. acknowledge the European Research Council (Grant Agreement 848325 ). B.B.M., H.I.K., H.Z. and M.G. contributed equally to this project. We than...
Biomimetic Ghost Nanomedicine-Based Optotheranostics for Cancer
Prasad, Rajendra; Jyothi, Vaskuri G.S.; Kommineni, Nagavendra; Bulusu, Ravi Teja; Mendes, Bárbara B.; Lovell, Jonathan F.; Conde, JoãoPublisher Copyright: © 2024 The Authors. Published by American Chemical Society.; Theranostic medicine combines diagnostics and therapeutics, focusing on solid tumors at minimal doses. Optically activated photosensitizers are significant examples owing to their photophysical and chemical properties. Several optotheranostics have been tested that convert light to imaging signals, therapeutic radicals, and heat. ...
Engineered Liposomes in Interventional Theranostics of Solid Tumors
Kommineni, Nagavendra; Chaudhari, Ruchita; Conde, João; Tamburaci, Sedef; Cecen, Berivan; Chandra, Pranjal; Prasad, RajendraFunding Information: R.P. thanks the director of IIT-BHU, Varanasi, U.P., for encouraging and providing the necessary facility and support and would also like to thank the school of biochemical engineering, IIT-BHU. N.K. would like to thank CBR, Population Council, for providing the Sheldon J. Segal Post-Doctoral Fellowship. P.C. acknowledges the support from the DST-funded I-DAPT Hub Foundation, IIT BHU [DST/N...
Conjugated Nanoparticles for Solid Tumor Theranostics
Chavda, Vivek P; Balar, Pankti C; Nalla, Lakshmi Vineela; Bezbaruah, Rajashri; Gogoi, Niva Rani; Gajula, Siva Nageswara Rao; Peng, Berney© 2023 The Authors. Published by American Chemical Society.; Cancer diagnoses have been increasing worldwide, and solid tumors are among the leading contributors to patient mortality, creating an enormous burden on the global healthcare system. Cancer is responsible for around 10.3 million deaths worldwide. Solid tumors are one of the most prevalent cancers observed in recent times. On the other hand, early dia...
Bioinspired and biomimetic cancer-cell-derived membrane nanovesicles for precli...
Prasad, Rajendra; Mendes, Bárbara B.; Gorain, Mahadeo; Chandra Kundu, Gopal; Gupta, Narendra; Peng, Berney; Aung Win, Eaint Honey; Qing, He; Conde, JoãoFunding Information: J.C. and B.M. acknowledge European Research Council grant agreement 848325 . R.P. would like to thank the Director, Indian Institute of Technology (BHU), Varanasi and the School of Biochemical Engineering, IIT (BHU) for support during preparation of this manuscript. We thank the Trident Diagnostics Center and staff for imaging and laser studies and NCCS, Pune for in vivo facilities. We woul...
Bioinspired soft nanovesicles for site-selective cancer imaging and targeted th...
Prasad, Rajendra; Conde, JoãoFunding Information: European Research Council, ERC Starting Grant, Grant/Award Number: ERC‐StG‐2019‐848325 Funding information Funding Information: This work is supported by the European Research Council, ERC Starting Grant ‐ ERC‐StG‐2019‐848325. The authors would like to thank Dr. N. K. Jain, Dr. S. Meena, and Dr. Gorain for glancing at this article. We would like to dedicate this article to the memory of lat...
Nucleic acid-based therapy for brain tumor
Zhang, Zixia; Conniot, João; Amorim, Joana; Jin, Yiliang; Prasad, Rajendra; Yan, Xiyun; Fan, Kelong; Conde, JoãoThis work was financially supported by the National Key Research and Development Program of China (No. 2021YFA1201102), the European Research Council Starting Grant (ERC-StG-2019-848325 to J. Conde), National Natural Science Foundation of China (No. 82122037, No. 31900981), the Strategic Priority Research Program of CAS (XDB29040101), Youth Innovation Promotion Association of Chinese Academy of Sciences (201909...
Ultrahigh Penetration and Retention of Graphene Quantum Dot Mesoporous Silica N...
Prasad, Rajendra; Jain, Nishant K.; Yadav, Amit S.; Jadhav, Manali; Radharani, Nalukurthi Naga Venkata; Gorain, Mahadeo; Kundu, Gopal C.; Conde, JoãoFunding: This work was supported by Department of Biotechnology, Government of India. J.C. acknowledges the European Research Council Starting Grant (ERC-StG-2019-848325). We thank the staff of animal house, NCCS, Pune for supporting us during animal studies. We also thank Mr. Sumit for the discussion and Dr. Mukesh K. Kumawat for providing GQDs.; So far, near-infrared (NIR) light responsive nanostructures have...
Liposomal nanotheranostics for multimode targeted in vivo bioimaging and near‐i...
Prasad, Rajendra; Jain, Nishant K.; Yadav, Amit S.; Chauhan, Deepak S.; Devrukhkar, Janhavi; Kumawat, Mukesh K.; Shinde, Shweta; Gorain, MahadeoDeveloping a nanotheranostic agent with better image resolution and high accumulation into solid tumor microenvironment is a challenging task. Herein, we established a light mediated phototriggered strategy for enhanced tumor accumulation of nanohybrids. A multifunctional liposome based nanotheranostics loaded with gold nanoparticles (AuNPs) and emissive graphene quantum dots (GQDs) were engineered named as NFG...