16 documents found, page 1 of 2
Prevalence of multiple sclerosis in key cities of Brazil. A study in Joinville,...
Gonçalves,Marcus Vinícius Magno; Siquineli,Fábio; Ribas,Flavio Diniz; Longo,Alexandre Luiz; Amaral,Claudio Henrique do; Chikota,Edila MiersABSTRACT Background: The Brazilian Committee for Treatment and Research in Multiple Sclerosis (BCTRIMS) has launched an initiative to determine the prevalence of multiple sclerosis (MS) in Brazil, based on key cities deemed representative of their regions in terms of demographic and environmental features. Objective: To investigate the prevalence rate of MS in Joinville. Methods: We reviewed the medical records...
Evaluation of diagnosis and treatment practices of Brazilian neurologists among...
Marin,Cássia Elisa; Callegaro,Dagoberto; Lana-Peixoto,Marco Aurélio; Fernández,Oscar; Gomes Neto,Antonio Pereira; Vasconcelos,Claudia Cristina FerreiraABSTRACT Background: Recent changes to the diagnostic criteria for multiple sclerosis (MS) and new medications have had a major impact on the way in which specialists manage the disease. Objective: To investigate factors considered by Brazilian neurologists in managing MS, and to identify how these contribute to diagnosis and treatment. Methods: Potential participants were selected by a steering committee (MS e...
Prevalence of multiple sclerosis in key cities of Brazil: a study in Passo Fund...
Passos,Giordani Rodrigues dos; Becker,Jefferson; Varela,Daniel Lima; Fröhlich,Alan Christmann; Rech,Bruna Constantino; Mattos,Ana Carolina Squeff deABSTRACT Background: To improve the comparability of multiple sclerosis (MS) prevalence across Brazilian regions, the Brazilian Committee for Treatment and Research in MS has implemented a standardized approach to assess the prevalence of the disease in five key cities, which were deemed representative of their regions in terms of socio-geographical features and where in-person revision of each case was feasibl...
Recommendations by the Scientific Department of Neuroimmunology of the Brazilia...
Becker,Jefferson; Ferreira,Lis Campos; Damasceno,Alfredo; Bichuetti,Denis Bernardi; Christo,Paulo Pereira; Callegaro,DagobertoABSTRACT The Scientific Department of Neuroimmunology of the Brazilian Academy of Neurology (DCNI/ABN) and Brazilian Committee for Treatment and Research in Multiple Sclerosis and Neuroimmunological Diseases (BCTRIMS) provide recommendations in this document for vaccination of the population with demyelinating diseases of the central nervous system (CNS) against infections in general and against the severe acut...
Normative values of the Brief Repeatable Battery of Neuropsychological Tests in...
Damasceno,Alfredo; Amaral,Juliana Machado Santiago dos Santos; Barreira,Amilton Antunes; Becker,Jefferson; Callegaro,Dagoberto; Campanholo,Kenia RepisoABSTRACT Objective Cognitive dysfunction is common in multiple sclerosis. The Brief Repeatable Battery of Neuropsychological Tests (BRB–N) was developed to assess cognitive functions most–frequently impaired in multiple sclerosis. However, normative values are lacking in Brazil. Therefore, we aimed to provide continuous and discrete normative values for the BRB–N in a Brazilian population sample. Methods We rec...
Brazilian Consensus for the Treatment of Multiple Sclerosis: Brazilian Academy ...
Marques,Vanessa Daccach; Passos,Giordani Rodrigues dos; Mendes,Maria Fernanda; Callegaro,Dagoberto; Lana-Peixoto,Marco AurélioABSTRACT The expanding therapeutic arsenal in multiple sclerosis (MS) has allowed for more effective and personalized treatment, but the choice and management of disease-modifying therapies (DMTs) is becoming increasingly complex. In this context, experts from the Brazilian Committee on Treatment and Research in Multiple Sclerosis and the Neuroimmunology Scientific Department of the Brazilian Academy of Neurolo...
Basal cortisol levels and the relationship with clinical symptoms in multiple s...
Pereira,Gabriela Magalhães; Soares,Nayron Medeiros; Souza,Andreo Rysdyk de; Becker,Jefferson; Finkelsztejn,Alessandro; Almeida,Rosa Maria Martins deABSTRACT Multiple sclerosis (MS) is a demyelinating, progressive and neurodegenerative disease. A disturbance on the hypothalamic-pituitary-adrenal axis can be observed in patients with MS, showing altered cortisol levels. We aimed to identify basal cortisol levels and verify the relationship with clinical symptoms in patients with MS. A systematic search was conducted in the databases: Pubmed, Web of Science a...
MOG-IgG associated optic neuritis is not multiple sclerosis
Costa,Bruna Klein da; Passos,Giordani Rodrigues dos; Becker,Jefferson; Sato,Douglas KazutoshiABSTRACT Autoantibodies against myelin oligodendrocyte glycoprotein (MOG-IgG) have been reported in patients with inflammatory central nervous system disorders including isolated optic neuritis (ON). We compared our MOG-IgG ON patients with multiple sclerosis (MS) patients presenting with ON. Methods and results: Among the total of 38 patients with optic neuropathies, six patients with isolated ON were MOG-IgG ...
Safety of switching from natalizumab straight into fingolimod in a group of JCV...
Fragoso,Yara Dadalti; Alves-Leon,Soniza Vieira; Becker,Jefferson; Brooks,Joseph Bruno Bidin; Correa,Eber Castro; Damasceno,Alfredo; Gama,Paulo Diniz daABSTRACT Objective To assess safety of the switch between natalizumab and fingolimod without a washout period. Methods Prospective data on 25 JCV positive patients who underwent this medication switch were collected and analyzed. Results After a median period of nine months from the medication switch, there were no safety issues to report. The patients had good disease control and no adverse events were reporte...
Nearly one-half of Brazilian patients with multiple sclerosis using natalizumab...
Fragoso,Yara Dadalti; Mendes,Maria Fernanda; Arruda,Walter Oleschko; Becker,Jefferson; Brooks,Joseph Bruno Bidin; Carvalho,Margarete de JesusObjective Natalizumab is a new and efficient treatment for multiple sclerosis (MS). The risk of developing progressive multifocal leukoencephalopathy (PML) during the use of this drug has created the need for better comprehension of JC virus (JCV) infection. The objective of the present study was to assess the prevalence of JCV-DNA in Brazilian patients using natalizumab. Method Qualitative detection of the JCV...