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MET is required for the recruitment of anti-tumoural neutrophils
Finisguerra, Veronica; Conza, Giusy Di; Matteo, Mario Di; Serneels, Jens; Costa, Sandra Maria Araújo da; Thompson, A. A. Roger; Wauters, ElsMutations or amplification of the MET proto-oncogene are involved in the pathogenesis of several tumours, which rely on the constitutive engagement of this pathway for their growth and survival. However, MET is expressed not only by cancer cells but also by tumour-associated stromal cells, although its precise role in this compartment is not well characterized. Here we show that MET is required for neutrophil c...
Date: 2015
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Origin: RepositóriUM - Universidade do Minho