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Exploring toxicological interactions in a changing sea: the case of the alkaloi...

Russo, Tania; Coppola, Francesca; Paris, Debora; De Marchi, Lucia; Meucci, Valentina; Motta, Andrea; Carbone, Marianna; Di Cosmo, Anna

The bisindolic alkaloid caulerpin (CAU) is a bioactive compound isolated from green algae of the genus Caulerpa that are highly invasive in the Mediterranean Sea. On the other side, the purine alkaloid caffeine (CAF) is one of the most globally consumed psychoactive substances and a widespread anthropogenic water pollutant. Both compounds display a large panel of biological properties and are well known to accu...


Combined effects of temperature rise and sodium lauryl sulfate in the Mediterra...

Freitas, Rosa; Arrigo, Federica; Coppola, Francesca; Meucci, Valentina; Battaglia, Federica; Soares, Amadeu M V M; Pretti, Carlo; Faggio, Caterina

Personal care products (PCPs) are those compounds used daily (e.g., soaps, shampoos, deodorants, and toothpaste), explaining their frequent detection in aquatic systems. Still, scarce information is available on their effects on inhabiting wildlife. Among the most commonly used PCPs is the surfactant Sodium Lauryl Sulfate (SLS). The present study investigated the influence of temperature (CTL 17 ºC vs 22 ºC) on...


Can temperature influence the impacts induced in Mytilus galloprovincialis by n...

Leite, Carla; Coppola, Francesca; Queirós, Vanessa; Russo, Tania; Polese, Gianluca; Pretti, Carlo; Pereira, Eduarda; Freitas, Rosa

Climate change-associated factors and pollutants, such as rare earth elements (REEs), have been identified as contributors to environmental changes. However, the toxicity resulting from the combination of these stressors has received little attention. Neodymium (Nd) is a REE that has been widely used, and this study aimed to evaluate the responses of Mytilus galloprovincialis to Nd exposure (10 µg/L), under act...


Can temperature rise change the impacts induced by e-waste on adults and sperm ...

Leite, Carla; Russo, Tania; Cuccaro, Alessia; Pinto, João; Polese, Gianluca; Soares, Amadeu M. V. M.; Pretti, Carlo; Pereira, Eduarda; Freitas, Rosa

Nowadays, it is of utmost importance to consider climate change factors, such as ocean warming, since the risk of negative impacts derived from increased surface water temperature is predicted to be high to the biodiversity. The need for renewable energy technologies, to reduce greenhouse gas emissions, has led to the increasing use of rare earth elements (REEs). Dysprosium (Dy) is widely used in magnets, motor...


Sub-lethal effects induced in Mytilus galloprovincialis after short-term exposu...

Paciello, Sofia; Russo, Tania; De Marchi, Lucia; Soares, Amadeu M. V. M.; Meucci, Valentina; Pretti, Carlo; He, Yide; Della Torre, Camila; Freitas, Rosa

Surfactants are among the most common PPCPs that reach coastal systems, being often used in large quantities in cleaning products such as detergents and soap powders. Sodium lauryl sulfate (SLS) is listed in this group of emerging contaminants. Previous studies have already demonstrated the presence of SLS in aquatic environments and the negative effects on organisms living there. However, with ocean acidificat...


Ecotoxicological screening of UV-filters using a battery of marine bioassays

Vieira Sanches, Matilde; Oliva, Matteo; De Marchi, Lucia; Cuccaro, Alessia; Puppi, Dario; Chiellini, Federica; Freitas, Rosa; Pretti, Carlo

The present study aimed to assess the toxicity of seven UV-filters: zinc oxide nanoparticles (nZnO, particle size <100 nm), titanium dioxide nanoparticles (nTiO2, primary particle size 21 nm), 2-ethylhexyl-4-methoxycinnamate (EHMC), 4-methylbenzylidene camphor (4-MBC), avobenzone (AVO), octocrylene (OCTO) and benzophenone-3 (BP-3) on three species: Aliivibrio fischeri (inhibition of bioluminescence), Phaeodacty...


The influence of salinity on sodium lauryl sulfate toxicity in Mytilus gallopro...

Freitas, Rosa; Coppola, Francesca; Meucci, Valentina; Battaglia, Federica; Soares, Amadeu M. V. M.; Pretti, Carlo; Faggio, Caterina

The influence of salinity on the effects of sodium lauryl sulfate (SLS) was evaluated using the Mediterranean mussel Mytilus galloprovincialis, exposed for 28 days to SLS (control-0.0 and 4.0 mg/L) under three salinity levels (Control-30, 25 and 35). The effects were monitored using biomarkers related to metabolism and energy reserves, defence mechanisms (antioxidant and biotransformation enzymes) and cellular ...


Toxicity Going Nano: Ionic Versus Engineered Cu Nanoparticles Impacts on the Ph...

Franzitta, Marco; Feijão, Eduardo; Cabrita, Maria Teresa; Gameiro, Carla; Matos, Ana Rita; Marques, João Carlos; Goessling, Johannes W.

Increasing input of Metal Engineered Nano Particles (MeENPs) in marine ecosystems has raised concerns about their potential toxicity on phytoplankton. Given the lack of knowledge on MeENPs impact on these important primary producers, the effects of Copper Oxide (CuO) ENPs on growth, physiology, pigment profiles, fatty acid (FA) metabolism, and oxidative stress were investigated in the model diatom Pheodactylum ...


Relationship between wild-caught organisms for bioassays and sampling areas: Wi...

Sanches, Matilde Vieira; Oliva, Matteo; Pires, Adília; De Marchi, Lucia; Cuccaro, Alessia; Freitas, Rosa; Baratti, Mariella; Pretti, Carlo

Previous studies suggested the suitability of the brackish-water serpulid (Ficopomatus enigmaticus) to be used as model organism for both marine and brackish waters monitoring, by the performance of sperm toxicity and larval development assays. The present study focused on larval development after the exposure of two F. enigmaticus populations (Mediterranean and Atlantic, collected in Italy and Portugal, respec...


The influence of climate change related factors on the response of two clam spe...

Costa, Silvana; Coppola, Francesca; Pretti, Carlo; Intorre, Luigi; Meucci, Valentina; Soares, Amadeu M. V. M.; Freitas, Rosa; Solé, Montserrat

Diclofenac (DIC) is one of the non-steroidal anti-inflammatory drugs (NSAID) with higher consumption rates, used in both human and veterinary medicine. Previous studies already demonstrated the presence of this drug in aquatic environments and adverse effects towards inhabiting organisms. However, with the predictions of ocean acidification and warming, the impacts induced by DIC may differ from what is present...


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