2 documents found, page 1 of 1
Vancomycin-Loaded, Nanohydroxyapatite-Based Scaffold for Osteomyelitis Treatmen...
Alegrete, N; Sousa, SR; Padrão, T; Carvalho, A; Lucas, R; Canadas, RF; Lavrador, C; Alexandre, N; Gärtner, F; Monteiro, FJ; Gutierres, MThe treatment for osteomyelitis consists of surgical debridement, filling of the dead space, soft tissue coverage, and intravenous administration of antimicrobial (AM) agents for long periods. Biomaterials for local delivery of AM agents, while providing controllable antibiotic release rates and simultaneously acting as a bone scaffold, may be a valuable alternative; thus, avoiding systemic AM side effects. V-H...
Phage Display Identified Peptide with Selectivity for Human Osteoarthritic Chon...
Martins, IM; Canadas, RF; Pereira, H; Azeredo, J; Reis, RL; Oliveira, JM; Azevedo, HSOsteoarthritis (OA) is one of the most common joint disorders in western populations, affecting millions of people worldwide and with a rising incidence as life expectancy continues to increase. Current therapies for OA management fail to halt the progressive degradation of articular cartilage, urging the need for more effective therapies to improve function and enhance quality of life. Through phage display te...