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Beyond clinical trials – The cost saving associated with dapagliflozin use in P...

Brito, Dulce; Fonseca, Cândida; Franco, Fátima; Lopes, Vanessa; Gonçalves, Sara; Baptista, Rui; Sequeira, Joana; Marques, Irene; Rego, Rita

Publisher Copyright: © 2024 Sociedade Portuguesa de Cardiologia; Introduction and objectives: Heart failure (HF) is a clinical syndrome associated with substantial morbidity, mortality, and healthcare costs. Dapagliflozin has proven efficacy in reducing the risk of death and hospitalization in HF patients, regardless of left ventricular ejection fraction (LVEF). This paper aimed to project the potential impact ...


A dynamic difficulty adjustment model for dysphonia therapy games

Lopes, Vanessa; Magalhães, João; Cavaco, Sofia

CMUP-ERI/TIC/0033/2014; Studies on childhood dysphonia have revealed considerable rates for voice disorders in 4 – 12 year-old children. The sustained vowel exercise is widely used as a technique in the vocal (re)education process. However this exercise can become tedious after a short practice. Here, we propose a novel dynamic difficulty adjustment model to be used in a serious game with the sustained vowel ex...


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