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Relationship between Fusobacterium nucleatum, inflammatory mediators and microR...
Proença, Marcela Alcântara; Biselli, Joice Matos; Succi, Maysa; Severino, Fábio Eduardo; Berardinelli, Gustavo Noriz; Caetano, Alaor; Reis, R. M.AIM To examine the effect of Fusobacterium nucleatum (F. nucleatum) on the microenvironment of colonic neoplasms and the expression of inflammatory mediators and microRNAs (miRNAs). METHODS Levels of F. nucleatum DNA, cytokine gene mRNA (TLR2, TLR4, NFKB1, TNF, IL1B, IL6 and IL8), and potentially interacting miRNAs (miR-21-3p, miR-22-3p, miR-28-5p, miR-34a-5p, miR-135b-5p) were measured by quantitative polymera...
Date: 2018
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Origin: RepositóriUM - Universidade do Minho