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Determinants of HIV-1 Transmission Clusters and Transmitted Drug Resistance in ...

Abrantes, Ricardo; Pimentel, Victor; Sebastião, Cruz; Miranda, Mafalda N S; Seabra, Sofia; Silva, Ana Rita; Diniz, António; Ascenção, Bianca

Introduction: In the EU/EEA, men who have sex with men (MSM) is a priority group for the prevention and control of HIV-1 infection. In Portugal, the 2023 HIV incidence rate was 8.2 per 100,000 inhabitants, with 876 new infections, 41.7% in MSM. We aim to characterize HIV-1 transmission clusters (TC) and transmitted drug resistance (TDR) and its sociodemographic, behavioral, clinical, and viral genomic determina...


Determinants of HIV-1 transmission clusters and transmitted drug resistance in ...

Abrantes, Ricardo; Pimentel, Victor; Sebastião, Cruz; Miranda, Mafalda N. S.; Seabra, Sofia; Silva, Ana Rita; Diniz, António; Ascenção, Bianca

In the EU/EEA, men who have sex with men (MSM) is a priority group for the prevention and control of HIV-1 infection. In Portugal, the 2023 HIV incidence rate was 8.2 per 100,000 inhabitants, with 876 new infections, 41.7% in MSM. We aim to characterize HIV-1 transmission clusters (TC) and transmitted drug resistance (TDR) and its sociodemographic, behavioral, clinical, and viral genomic determinants in MSM new...


Determinação de rivastigmina, inibidor seletivo da colinesterase cerebral, em a...

Proença, Paula; Castanheira, Alice; Mustra, Carla; Castanheira, Fernando; Franco, João Miguel; Corte Real Gonçalves, Francisco

Intodução: Sempre que ocorre uma situação relevante de pesquisa de um fármaco não incluído no leque de substâncias detetadas, o laboratório dedica-se a implementar a sua técnica de modo a poder ser dada uma resposta à perícia solicitada. A rivastigmina é um inibidor das colinesterases do tipo carbamato, utilizada no tratamento de demência associada à doença de Alzheimer e à doença de Parkinson. Material e Métod...


Importância forense dos fármacos que atuam no aparelho cardiovascular. O top 5 ...

Mustra, Carla; Proença, Paula; Castanheira, Alice; Castanheira, Fernando; Monsanto, Paula; Franco, João Miguel

INTRODUÇÃO: A pesquisa de medicamentos, drogas e álcool constituem a maioria das perícias realizadas no Serviço de Química e Toxicologia Forenses (SQTF). O desenvolvimento de novos métodos de análise ou melhoria da capacidade de deteção de substâncias novas ou já existentes é uma constante neste serviço, pelo que a avaliação estatística dos resultados e a atualização da informação relativamente a novas tendênci...


Suicide by self-administration of pethidine, propofol and anxiolytics : a case ...

Proença, Paula; Castanheira, Alice; Castanheira, Fernando; Monteiro, Carla; Simoes Da Silva, Beatriz; Franco, João Miguel; Corte Real, Francisco

Background and aim: Recreational use of anesthetic and sedative agents in health care practitioners is becoming an increasing problem due to its easy availability and, therefore, they become vulnerable to misusing or abusing of these drugs. The authors present a fatal case involving a a 50-year-old man, nurse, found dead in a hospital room, in supine position, with intravenous access devices in the forearm that...


Sociodemographic, Clinical, and Behavioral Factors Associated with Sexual Trans...

Miranda, Mafalda N. S.; Pimentel, Victor; Graça, Jacqueline; Seabra, Sofia G.; Sebastião, Cruz S.; Diniz, António; Faria, Domitília; Teófilo, Eugénio

Introduction: Sexually transmitted infections (STIs) continue to occur at high levels. According to the WHO, each year there are an estimated 374 million new infections with syphilis, gonorrhea, chlamydia, and trichomoniasis. STIs are associated with an increased risk of acquiring HIV infection. Migrants are reportedly highly affected by STIs. Objectives: This study aims to characterize factors associated with ...


Determinants of HIV late presentation among men who have sex with men in Portug...

Abrantes, Ricardo; Pimentel, Victor; Miranda, Mafalda N. S.; Silva, Ana Rita; Diniz, António; Ascenção, Bianca; Piñeiro, Carmela; Koch, Carmo

Introduction: HIV late presentation (LP) remains excessive in Europe. We aimed to analyze the factors associated with late presentation in the MSM population newly diagnosed with HIV in Portugal between 2014 and 2019. Methods: We included 391 newly HIV-1 diagnosed Men who have Sex with Men (MSM), from the BESTHOPE project, in 17 countrywide Portuguese hospitals. The data included clinical and socio-behavioral q...


Determinants of HIV late presentation among men who have sex with men in Portug...

Abrantes, Ricardo; Pimentel, Victor; Miranda, Mafalda N. S.; Silva, Ana Rita; Diniz, António; Ascenção, Bianca; Piñeiro, Carmela; Koch, Carmo

Introduction HIV late presentation (LP) remains excessive in Europe. We aimed to analyze the factors associated with late presentation in the MSM population newly diagnosed with HIV in Portugal between 2014 and 2019.Methods We included 391 newly HIV-1 diagnosed Men who have Sex with Men (MSM), from the BESTHOPE project, in 17 countrywide Portuguese hospitals. The data included clinical and socio-behavioral ques...


Sociodemographic, clinical, and behavioral factors associated with sexual trans...

Miranda, Mafalda N. S.; Pimentel, Victor; Graça, Jacqueline; Seabra, Sofia G.; Sebastião, Cruz S.; Diniz, António; Faria, Domitília; Teófilo, Eugénio

Introduction: Sexually transmitted infections (STIs) continue to occur at high levels. According to the WHO, each year there are an estimated 374 million new infections with syphilis, gonorrhea, chlamydia, and trichomoniasis. STIs are associated with an increased risk of acquiring HIV infection. Migrants are reportedly highly affected by STIs. Objectives: This study aims to characterize factors associated with ...


A retrospectÍve analysis of data from cannabinoid forensic cases in the Centre ...

Proença, Paula; Teixeira, Helena M.; Monteiro, Carla; Monsanto, Paula; Coelho, Maria; Franco, João Miguel; Corte Real, Francisco

Background and aim: Marijuana, hashish and other psychoactive products obtained from Cannabis are the most produced and trafficked illicit drugs around the world. Methods: The authors studied all the positive cases for cannabinoids in the Centre of Portugal; from autopsies at the Forensic Clinical and Pathology Service of Coimbra’s Delegation of the National Institute of Legal Medicine and Forensic Sciences (NI...


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