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The 2021 Portuguese Society of Ophthalmology Joint Guidelines with Paediatric R...
Leal, I; Miranda, V; Fonseca, C; Barbosa-Breda, J; Cordeiro Sousa, D; Mesquita-Marques, P; Araújo, J; Silva, MI; Pedrosa, AC; Palmares, J; Furtado, MJAim: To develop the first Ophthalmology joint guidelines with Paediatric Rheumatology with recommendations on the screening, monitoring and medical treatment of juvenile idiopathic arthritis-associated uveitis (JIA-U), endorsed by the Portuguese Society of Ophthalmology (SPO). Methods: A systematic literature review was conducted to include publications up to July 14th 2020, with no language restrictions, in or...
Ocular Involvement in Systemic Lupus Erythematosus Patients: a Paradigm Shift B...
Dias-Santos, A; Ferreira, J; Pinheiro, S; Cunha, JP; Alves, M; Papoila, AL; Moraes-Fontes, MF; Proença, RObjective: To evaluate ocular involvement in a cohort of systemic lupus erythematosus (SLE) patients of a tertiary referral center and to compare the results with the existing literature. Methods: Patients underwent a complete ophthalmological evaluation, including visual acuity, slit-lamp examination, fluorescein staining, Schirmer-I test, Goldmann applanation tonometry, fundoscopy, 10-2 automated threshold vi...
Ocular Ischaemia Due to a Spontaneous Carotid Artery Dissection
Frazão, S; Perry da Câmara, C; Proença, R; Tavares Ferreira, JInternal carotid artery dissection (ICAD) is caused by the disruption of the tunica intima, with the formation of an intramural haematoma that can cause stenosis or occlusion of the artery's lumen, leading to reduced blood flow and secondary thrombus formation. Up to two-thirds of patients with ICAD show ophthalmological symptoms or signs, which are, frequently, the first manifestations of this clinical conditi...
Orbital Metastasis from an Occult Breast Carcinoma (T0, N1, M1)
Pinto Proença, R; Fernandes, J; Burnier, M; Proença, RThe authors report a case of an orbital metastasis from an occult breast carcinoma. A 66-year-old woman presented with a growing left orbital tumour. Orbital CT scan was consistent with lymphoma. However, ocular pathology revealed small neoplastic cells showing an 'indian file pattern' suggestive of metastatic carcinoma and immunohistochemistry was positive for CK7, CK CAM5.2 and oestrogen receptor. A systemic ...
The Role of Ophthalmic Imaging in Central Nervous System Degeneration in System...
Dias-Santos, A; Proença, R; Tavares Ferreira, J; Pinheiro, S; Cunha, JP; Proença, R; Moraes-Fontes, MFSystemic lupus erythematosus (SLE) is an autoimmune connective tissue disorder that can involve any organ system. Central nervous system involvement can be a severe life threatening complication, ultimately resulting in severe neurodegenerative changes. Magnetic resonance imaging suggests that neurodegeneration, which may have deleterious effects on brain function, may occur early in SLE and experimental models...
Conjunctival Melanoma: Association of Cyclooxygenase-2 Tumor Expression to Prog...
Proença, R; Santos, M; Fonseca, C; Fernandes, J; Gaspar, MF; Proença, RPURPOSE: Conjunctival melanoma is a rare but potentially lethal tumor. Its biologic profile is still largely unknown, with recent studies aiming at establishing histopathological and genetic tumor profiles. The aim of this study was to analyze the association between clinicopathological characteristics and tumor expression of cyclooxygenase-2 (COX-2) to prognosis, assessing its usefulness as a possible prognost...
Choroidal Thinning: Alzheimer's Disease and Aging
Cunha, JP; Proença, R; Dias-Santos, A; Melancia, D; Almeida, R; Águas, H; Oliveira Santos, B; Alves, M; Ferreira, J; Papoila, AL; Louro, CINTRODUCTION: The purpose of this study was to measure and to compare macular choroidal thickness (CT) between patients with mild Alzheimer's disease (AD), patients without AD, and elderly patients. METHODS: CT was measured manually in 13 locations at 500-μm intervals of a horizontal and a vertical section from the fovea. Linear regression models were used to analyze the data. RESULTS: Fifty patients with a dia...
OCT in Alzheimer's Disease: Thinning of the RNFL and Superior Hemiretina
Cunha, JP; Proença, R; Dias-Santos, A; Almeida, R; Águas, H; Alves, M; Papoila, AL; Louro, C; Castanheira-Dinis, ABACKGROUND: Peripapillary retinal nerve fiber layer (pRNFL) and internal macular layer thinning have been demonstrated in Alzheimer's disease (AD) with optical coherence tomography (OCT) studies. The purpose of this study is to compare the pRNFL thickness and overall retinal thickness (RT) in AD patients with non-AD patients, using spectral domain optical coherence tomography (SD-OCT) and determine the sectors ...
Melanoma da Coroideia
Coutinho, I; Teixeira, T; Simões, C; Lopes, C; Borrego, M; Fernandes, J; Cabral, J; Prieto, I; Proença, RChoroidal melanoma is the most common primary intraocular malignant tumor in adults. None of the different treatments available offers advantages of survival, resorting more and more to conservative treatments such as brachytherapy, which has been available in Portugal since 2013. In this article we review the clinical characteristics, risk factors, diagnosis, complementary exams and therapeutic options in chor...
Retina and Choroid of Diabetic Patients Without Observed Retinal Vascular Chang...
Ferreira, J; Proença, R; Alves, M; Dias-Santos, A; Santos, B; Cunha, JP; Papoila, AL; Abegão Pinto, LPURPOSE: To identify changes in choroidal thickness (CT) and all retinal layers of diabetic patients without diabetic retinopathy (DR) after 1 year of follow-up. DESIGN: Prospective observational cohort study. METHODS: Overall, 125 diabetic patients without DR were included. Two visits were scheduled: the first visit (V1) and a second visit after 12 months (V2). At both visits, patients received a complete opht...