ABSTRACT Purpose: To translate and validate the Contact Lens Dry Eyes Questionnaire (CLDEQ-8) to Portuguese language and to describe the impact of soft contact lenses on the ocular surface. Methods: We conducted a descriptive transversal study with the aim to: (1) translate and validate the CLDEQ-8 questionnaire to Portuguese language and (2) apply the CLDEQ-8 to a group of contact lens wearers along with a bro...
ABSTRACT Objective: This research presents a biomechanical analysis performed in the lumbar spine of a porcine animal model, considering a minimally invasive technique for the treatment of split fractures. Methods: Porcine spines were used to perform compression tests, considering three different approaches. Three groups were defined in order to verify and validate the proposed technique: a control group (1); s...
ABSTRACT Objective: To evaluate a new treatment for split fractures through fatigue tests on a swine model. Methods: Thirty lumbar spine samples (L2-L3-L4) from swine models were divided into three test groups. The first was the control group (intact vertebrae). In the second group, a bone defect was created, similar to a coronal split fracture of the vertebral body. For this, a bone defect (osteotomy) was perf...
Resumo Fundamento Nos últimos anos, o recente aumento no número de procedimentos intervencionistas tem resultado em crescente preocupação em relação à exposição radiológica por pacientes e equipe médica. A avaliação da exposição dos níveis de radiação em crianças é difícil devido à grande variabilidade no peso corporal. Portanto, os valores de referência de radiação não estão bem definidos para essa população. ...
Resumo Contexto A síndrome de May-Thurner (SMT) é a compressão da veia ilíaca esquerda (VIE) entre a artéria ilíaca direita e o corpo vertebral associada à hipertensão venosa crônica unilateral no membro inferior esquerdo. Porém, o achado tomográfico da compressão não necessariamente se reflete em sintomas. Objetivos Avaliar o achado de compressão da veia ilíaca esquerda em tomografias realizadas por outros mot...
Abstract Introduction This study describes the epidemiological scenario of human immunodeficiency virus (HIV) and syphilis at the biggest specialist drug addiction center in Brazil. The great challenge is to find strategies to reduce the impact of inequality and discrimination and develop policies to protect individuals living with – or at risk of – infections. Methods During the period from January 1 to May 31...
Objective: Cocaine use disorders (CUDs) represent a major public health problem in many countries. To better understand the interaction between the environmental modulations and phenotype, the aim of the present study was to investigate the DNA methylation pattern of CUD patients, who had concomitant cocaine and crack dependence, and healthy controls. Methods: We studied DNA methylation profiles in the peripher...
Cannabis is the most commonly used illegal drug, and is associated with well-documented adverse health outcomes, both acute and chronic. Cannabis use prevalence in Brazil is lower than in high-use regions in the Americas (e.g., North America), but concentrated among young people. Frameworks for cannabis control are increasingly shifting towards public health-oriented principles, with some countries undertaking ...
Abstract Introduction: The recovery housing (RH) program was initiated in São Paulo with the objective of providing treatment for substance use disorders and addressing users’ housing and employment problems. The purpose of this study was to describe the model based on its first 11 months of operation, it was launched in June 2016 in Brazil. Method: We carried out a retrospective analysis of the records of all ...
OBJETIVO: Avaliar a eficácia do efeito analgésico da vertebroplastia com polimetilmetacrilato (PMMA) e da estabilização vertebral obtida nos pacientes com fraturas vertebrais patológicas e realizar uma revisão detalhada da técnica da vertebroplastia percutânea, analisando suas indicações. MÉTODOS: Análise retrospectiva de 64 procedimentos de vertebroplastia percutânea em 46 pacientes. Foram realizadas avaliaçõe...