10 documents found, page 1 of 1
Plasma Metabolites Associated with OCT Features of Age-Related Macular Degenera...
Laíns, Inês; Han, Xikun; Gil, João; Providência, Joana; Nigalye, Archana; Alvarez, Rodrigo; Douglas, Vivian Paraskevi; Mendez, Kevin; Katz, RavivPurpose: The most widely used classifications of age-related macular degeneration (AMD) and its severity stages still rely on color fundus photographs (CFPs). However, AMD has a wide phenotypic variability that remains poorly understood and is better characterized by OCT. We and others have shown that patients with AMD have a distinct plasma metabolomic profile compared with controls. However, all studies to da...
Dual Retinitis with Cytomegalovirus and Herpes Simplex in a Paediatric Patient ...
Figueiredo, Inês; Providência, Joana; Fonseca, Cristina; Monteiro, Ana Madalena; Castela, GuilhermeHerpesvirus retinitis is a serious infection of the retina typically found in immunosuppressed patients. We report the case of a 4-year-old boy with a history of enucleation of the left eye for intraocular advanced retinoblastoma, at time under systemic adjuvant chemotherapy, observed under anaesthesia for periodic disease follow-up. Right eye fundus evaluation showed multiple areas of focal haemorrhagic retini...
Tocilizumab no Tratamento da Orbitopatia de Graves
Pereira, Pedro Nuno; Providência, Joana; Queirós, Tatiana; Ponces, Filipa; Castela, Guilherme; Murta, JoaquimIntrodução: A orbitopatia de Graves (GO) é uma doença inflamatória autoimune com tratamento desafiante e algo controverso. As opções terapêuticas na doença ativa moderada a grave podem incluir a terapêutica endovenosa com corticoides, outros imunomoduladores, radioterapia ou descompressão cirúrgica da órbita. O Clinical Activity Score (CAS) é uma escala clínica que quantifica os sinais e sintomas...
Effectiveness of Intra-Arterial Chemotherapy for the Treatment of Intraocular R...
Castela, Guilherme; Providência, Joana; Monteiro, Madalena; Oliveiros, Bárbara; Silva, Sónia; Brito, Manuel; Machado, Egídio; Murta, Joaquim NetoPurpose: We aim to report about effectiveness and safety in the context of our centers’ setting in the management of retinoblastoma with intra-arterial chemotherapy (IAC) in a 5-year retrospective analysis of the Portuguese population. Patients and Methods: Retrospective analysis of consecutive cases of retinoblastoma selected to initiate IAC between 2015 and 2020, at the Portuguese National Reference Center. A...
Optical Coherence Tomography (OCT) in Retinoblastoma Management: Experience of ...
Q. Dias, Margarida; Providência, Joana; Monteiro, Madalena; Castela, GuilhermeINTRODUCTION: Patients under 5 years old with retinoblastoma require close monitoring under anesthesia to ensure early detection of new tumors. They undergo monthly observations after diagnosis and during the first 6 months after treatment, then observations are gradually spaced in time until the age of five. Optical coherence tomography (OCT) is a relatively new exam in monitoring retinoblastoma patients. The ...
Characterization of the Portuguese population diagnosed with retinoblastoma
Castela, Guilherme; Providência, Joana; Monteiro, Madalena; Silva, Sonia; Brito, Manuel; Sá, Joaquim; Oliveiros, Bárbara; Murta, Joaquim NetoThe purpose of this study is to characterize demographically and genetically the Portuguese population with retinoblastoma; to report the clinical stage at presentation and its impact on survival and ocular preservation rate and, finally, to assess the incidence of retinoblastoma in Portugal. Retrospective observational study including children consecutively diagnosed with retinoblastoma at the Portuguese Natio...
Treatment of Advanced Retinoblastoma in Children Evacuated from Low-Income Coun...
Castela, Guilherme; Providência, Joana; Monteiro, Madalena; Silva, Sónia; Brito, Manuel; Murta, Joaquim Neto; Correa, Zélia; Castelo-Branco, MiguelObjective: The aim of our study was to characterize the evacuated African patients diagnosed with retinoblastoma and referred to the Portuguese national referral center (Centro Hospital e Universitário de Coimbra, University of Coimbra), identifying inequalities in the stage of diagnosis and prognostic results. Design: Retrospective observational study of evacuated African patients diagnosed with retinoblastoma...
Real-World Results of Aflibercept versus Ranibizumab for the Treatment of Exuda...
Providência, Joana; Rodrigues, Tiago M; Oliveira, Mariana; Bernardes, João; Marques, João Pedro; Murta, Joaquim N.; Silva, RufinoIntravitreal injections of antivascular endothelial growth factors have been considered a milestone in the treatment of neovascular age-related macular degeneration (nAMD). However, the increasing incidence of AMD and the burden of visits and injections overcharge both the patient and the healthcare systems. Real-world solutions depend on treatment protocols aimed at optimizing the number of clinical visits whi...
Diabetic Choroidopathy: Choroidal Vascular Density and Volume in Diabetic Retin...
Wang, Jay C.; Laíns, Inês; Providência, Joana; Armstrong, Grayson W.; B M Santos, Ana Rita; Gil, Pedro; Gil, João; Talcott, Katherine E.Purpose To compare choroidal vascular density (CVD) and volume (CVV) in diabetic eyes and controls, using en face swept-source optical coherence tomography (SS-OCT). Design Prospective cross-sectional study. Methods Setting: Multicenter. Patient Population: Total of 143 diabetic eyes—27 with no diabetic retinopathy (DR), 47 with nonproliferative DR (NPDR), 51 with NPDR and diabetic macular edema (DME), and 18 w...
É-me difícil falar de dança
Providência, Joanaé-me difícil falar sobre dança / de qualquer das formas passo a dar a ler textos escritos por mim, enquanto pensava nela / [(...)]