7 documents found, page 1 of 1
A global multinational survey of cefotaxime-resistant coliforms in urban wastew...
Marano, Roberto B. M.; Fernandes, Telma; Manaia, Célia M.; Nunes, Olga; Morrison, Donald; Berendonk, Thomas U.; Kreuzinger, Norbert; Tenson, TanelThe World Health Organization Global Action Plan recommends integrated surveillance programs as crucial strategies for monitoring antibiotic resistance. Although several national surveillance programs are in place for clinical and veterinary settings, no such schemes exist for monitoring antibiotic-resistant bacteria in the environment. In this transnational study, we developed, validated, and tested a low-cost...
Every fifth published metagenome is not available to science
Eckert, Ester M.; Cesare, Andrea Di; Fontaneto, Diego; Berendonk, Thomas U.; Bürgmann, Helmut; Cytryn, Eddie; Fatta-Kassinos, Despo; Franzetti, AndreaHave you ever sought to use metagenomic DNA sequences reported in scientific publications? Were you successful? Here, we reveal that metagenomes from no fewer than 20% of the papers found in our literature search, published between 2016 and 2019, were not deposited in a repository or were simply inaccessible. The proportion of inaccessible data within the literature has been increasing year-on-year. Noncomplian...
A global multinational survey of cefotaxime-resistant coliforms in urban wastew...
Marano, Roberto B.M.; Fernandes, Telma; Manaia, Célia M.; Nunes, Olga; Morrison, Donald; Berendonk, Thomas U.; Kreuzinger, Norbert; Tenson, TanelThe World Health Organization Global Action Plan recommends integrated surveillance programs as crucial strategies for monitoring antibiotic resistance. Although several national surveillance programs are in place for clinical and veterinary settings, no such schemes exist for monitoring antibiotic-resistant bacteria in the environment. In this transnational study, we developed, validated, and tested a low-cost...
Comparison of culture- and quantitative PCR-Based indicators of antibiotic resi...
Rocha, Jaqueline; Fernandes, Telma; Riquelme, Maria V.; Zhu, Ni; Pruden, Amy; Manaia, Célia M.Standardized methods are needed to support monitoring of antibiotic resistance in environmental samples. Culture-based methods target species of human-health relevance, while the direct quantification of antibiotic resistance genes (ARGs) measures the antibiotic resistance potential in the microbial community. This study compared measurements of tetracycline-, sulphonamide-, and cefotaxime-resistant presumptive...
Water and sanitation: an essential battlefront in the war on antimicrobial resi...
Burgmann, Helmut; Frigon, Dominic; Gaze, William H.; Manaia, Célia M.; Pruden, Amy; Singer, Andrew C.; Smets, Barth F.; Zhang, TongWater and sanitation represent a key battlefront in combatting the spread of antimicrobial resistance (AMR). Basic water sanitation infrastructure is an essential first step towards protecting public health, thereby limiting the spread of pathogens and the need for antibiotics. AMR presents unique human health risks, meriting new risk assessment frameworks specifically adapted to water and sanitation-borne AMR....
Reusing treated wastewater: consideration of the safety aspects associated with...
Hong, Ying; Julian, Timothy R.; Pype, Marie-Laure; Jiang, Sunny C.; Nelson, Kara L.; Graham, David; Pruden, Amy; Manaia, Célia M.As more countries engage in water reuse, either intended or de facto, there is an urgent need to more comprehensively evaluate resulting environmental and public health concerns. While antibiotic-resistant bacteria (ARB) and antibiotic resistance genes (ARGs) are increasingly coming under the spotlight, as emerging contaminants, existing water reuse regulations and guidelines do not adequately address these con...
Toward a comprehensive strategy to mitigate dissemination of environmental sour...
Vikesland, Peter J.; Pruden, Amy; Alvarez, Pedro J. J.; Aga, Diana; Bürgmann, Helmut; Li, Xiang-dong; Manaia, Célia M.; Nambi, IndumathAntibiotic resistance is a pervasive global health threat. To combat the spread of resistance, it is necessary to consider all possible sources and understand the pathways and mechanisms by which resistance disseminates. Best management practices are urgently needed to provide barriers to the spread of resistance and maximize the lifespan of antibiotics as a precious resource. Herein we advise upon the need for...