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Neurophysiological features of primary lateral sclerosis

Carvalho, Mamede; Kiernan, Matthew C.; Pullman, Seth L; Rezania, Kourosh; Turner, MR; Simmons, Zachary

Primary lateral sclerosis (PLS) is a motor neuron disease characterized by spinobulbar spasticity, absence of progressive lower motor neuron (LMN) dysfunction and marked by a slow functional decline. Electromyography is essential to exclude significant LMN involvement, particularly in the context of distinguishing PLS from amyotrophic lateral sclerosis (ALS), given that the prognosis is substantially better, an...

Date: 2021   |   Origin: Repositório da Universidade de Lisboa
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