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Chasing the Effects of Pre-Analytical Confounders - A Multicenter Study on CSF-...

Leitão, Maria João; Baldeiras, Inês; Herukka, Sanna-Kaisa; Pikkarainen, Maria; Leinonen, Ville; Simonsen, Anja Hviid; Perret-Liaudet, Armand

Introduction: Core cerebrospinal fluid (CSF) biomarkers – Aβ42, Tau, and phosphorylated Tau (pTau) – have been recently incorporated in the revised criteria for Alzheimer’s disease (AD). However, their widespread clinical application lacks standardization. Preanalytical sample handling and storage play an important role in the reliable measurement of these biomarkers across laboratories. Aim: In this study, we ...

Date: 2015   |   Origin: Estudo Geral - Universidade de Coimbra
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