6 documents found, page 1 of 1
AGEs accumulation is related to muscle degeneration and vascular calcification ...
Fonseca,Laís de Faria; Araújo,Anna Beatriz; Quadros,Kélcia Rosana da Silva; Carbonara,Cinthia Esbrile Moraes; Dertkigil,Sérgio San JuanAbstract Background: Patients with chronic kidney disease (CKD) are affected by dynapenia, sarcopenia, and vascular calcification. Advanced glycation end products (AGEs) may accumulate in peritoneal dialysis (PD) patients and favor sarcopenia via changes in collagen cross-linking, muscle protein breakdown, and the calcification of arterial smooth muscle cells via p38-MAPK activation. The aim of this study is to...
Renal osteodystrophy and clinical outcomes: data from the Brazilian Registry of...
Carbonara,Cinthia Esbrile Moraes; Reis,Luciene Machado dos; Quadros,Kélcia Rosana da Silva; Roza,Noemi Angelica Vieira; Sano,RafaelABSTRACT Introduction: Mineral and bone disorders (MBD) are major complications of chronic kidney disease (CKD)-related adverse outcomes. The Brazilian Registry of Bone Biopsy (REBRABO) is an electronic database that includes renal osteodystrophy (RO) data. We aimed to describe the epidemiological profile of RO in a sample of CKD-MBD Brazilian patients and understand its relationship with outcomes. Methods: Bet...
The enigma of aluminum deposition in bone tissue from a patient with chronic ki...
Meira,Rodrigo Dias de; Carbonara,Cinthia Esbrile Moraes; Quadros,Kélcia Rosana da Silva; Santos,Carolina Urbini dos; Schincariol,PatríciaABSTRACT About four decades ago, the relationship between dialysis-dementia and aluminum (Al) began to be established. The restriction of drugs containing Al and improvements on water quality used for dialysis resulted in the clinical disappearance of Al intoxication. However, high prevalence of Al deposition in bone tissue from Brazilian dialysis patients is still being detected. Through the case report of a p...
Hypercalcemia in children: three cases report with unusual clinical presentations
Garbim,Bruna Barros; D´Ávila,Larissa; Rigatto,Sumara Zuanazi Pinto; Quadros,Kélcia Rosana da Silva; Belangero,Vera Maria SantoroAbstract Hypercalcemia is a rare condition in childhood; the most common causes are primary hyperparathyroidism, malignancy, prolonged immobilisation, thyrotoxicosis, thiazide diuretic, supplements containing calcium, milk-alkali syndrome, vitamin D intoxication, infections and idiopathic. We present three cases of severe hypercalcemia of unusual causes in children. The first patient had high fever, poor genera...
Advanced glycation end-products (AGEs) accumulation in skin: relations with chr...
França,Renata de Almeida; Esteves,André de Barros Albuquerque; Borges,Cynthia de Moura; Quadros,Kélcia Rosana da Silva; Falcão,Luiz Carlos NogueiraAbstract Introduction: Chronic kidney disease (CKD) is associated with high morbidity and mortality rates, main causes related with cardiovascular disease (CVD) and bone mineral disorder (CKD-BMD). Uremic toxins, as advanced glycation end products (AGEs), are non-traditional cardiovascular risk factor and play a role on development of CKD-BMD in CKD. The measurement of skin autofluorescence (sAF) is a noninvasi...
Patient in chronic hemodialysis with right atrial mass: thrombus, fungal endoca...
Salani,Talita G.; Borges,Cynthia de Moura; Urbini,Carolina S.; Schincariol,Patrícia; Quadros,Kélcia Rosana da Silva; Ribeiro-Alves,Maria AlmerindaAbstract We present the case report of a 19-year-old patient with chronic kidney disease due to chronic glomerulonephritis, in hemodialysis (HD) by central catheter, with the incidental finding of a mass of 28x16 mm in right atrium (RA). The diagnosis of thrombus, infective endocarditis or myxoma were considered. Given the context of immunosuppression and difficult access vascular therapeutic practice has prove...