2 documents found, page 1 of 1
Microglial Sirtuin 2 shapes long-term potentiation in hippocampal slices
Sa de Almeida, Joana; Vargas, Mariana; Fonseca-Gomes, João; Tanqueiro, Sara; Belo, Rita F.; Miranda-Lourenço, Catarina; Sebastião, Ana MCopyright © 2020 Sa de Almeida, Vargas, Fonseca-Gomes, Tanqueiro, Belo, Miranda-Lourenço, Sebastião, Diógenes and Pais. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this ...
Myeloid Sirtuin 2 expression does not impact long-term Mycobacterium tuberculos...
Cardoso, Filipa; Castro, Flávia Raquel Teixeira de; Moreira-Teixeira, Lúcia; Sousa, Jeremy Nicolas Carvalho; Torrado, EgídioSirtuins (Sirts) regulate several cellular mechanisms through deacetylation of several transcription factors and enzymes. Recently, Sirt2 was shown to prevent the development of inflammatory processes and its expression favors acute Listeria monocytogenes infection. The impact of this molecule in the context of chronic infections remains unknown. We found that specific Sirt2 deletion in the myeloid lineage tran...