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Chemical modifications of a natural xanthone and antimicrobial activity against...
Micheletti, Ana Camila; Honda, Neli Kika; Lima, Dênis Pires de; Beatriz, Adilson; Sant'ana, Maria Rita; Carvalho, Nádia Cristina PereiraA series of 15 ω-aminoalkoxylxanthones containing methyl, ethyl, propyl, tert-butylamino and piperidinyl moieties were synthesized from a natural xanthone isolated from a lichen species. These compounds were tested for their in vitro antibacterial properties against Gram-positive and Gram-negative bacteria and cytotoxicity against a number of human tumor cell lines was too evaluated. The newly synthesized deriv...
Date: 2011
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Origin: Oasisbr