Made available in DSpace on 2020-12-10T20:13:47Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-04-01; Inova Fundacao Oswaldo Cruz (FIOCRUZ); Background Bacterial meningitis (BM) causes apoptotic damage to the hippocampus and homocysteine (Hcy) accumulation to neurotoxic levels in the cerebrospinal fluid of children. The Hcy pathway controls bioavailability of methyl, and its homeostasis can be modulated...
Our goal was to carry out a comparative study to evaluate the metabolic and inflammatory effects and the redox status of commercial vegetable oils supplementation [linseed (LO), coconut (VCO), and sunflower (SO)] in metabolically healthy rats. The results found in this study showed that the LO group decreased the HOMA-IR and hepatic cholesterol, and increased the serum levels of IL-6. Supplementation with VCO i...
Endurance exercise is a remarkable intervention for the treatment of many diseases. Mitochondrial changes on skeletal muscle are likely important for many of the benefits provided by exercise. In this study, we aimed to evaluate the effects that a regular physical activity (swimming without workload) has on mitochondrial morphological alterations and glucometabolic parameters induced by a high-sugar diet (HSD)....
The mitochondrial uncoupling proteins (UCPs) of interscapular brown adipose tissue (iBAT) and of muscles play important roles in energy balance. For instance, the expression of UCP1 and UCP3 are modulated by free fatty acid gradients induced by high-sugar diets and acute exercise that is dependent on sympathetic stimulation. However, the effects of endurance training in animals fed with high-sugar diets are unk...
Programa de Pós-Graduação em Ciências Biológicas. Núcleo de Pesquisas em Ciências Biológicas, Pró-Reitoria de Pesquisa e Pós Graduação, Universidade Federal de Ouro Preto.; O presente trabalho teve como objetivo avaliar o efeito temporal de uma dieta rica em carboidratos simples (PTD), após o desmame, sobre o metabolismo do tecido adiposo retroperitoneal (TAR) de ratos jovens. Por questões didáticas, dividimos ...
O fenótipo de obesidade tem sido atribuído a questões multifatoriais. Uma dieta mal balanceada, associada ao sedentarismo, tem contribuído para a alta incidência da patologia, além de provocar alterações nos parâmetros plasmáticos do metabolismo de carboidratos e lipídeos. O objetivo deste trabalho foi avaliar a influência da dieta hiperglicídica em associação ao treinamento físico em esteira sobre a distribuiç...