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Localization of MCT2 at peroxisomes is associated with malignant transformation...
Valença, Isabel; Pértega-Gomes, Nelma; Rámon Vizcaino, José; Henrique, Rui M.; Lopes, Carlos; Baltazar, Fátima; Ribeiro, DanielaPrevious studies on monocarboxylate transporters expression in prostate cancer (PCa) have shown that monocarboxylate transporter 2 (MCT2) was clearly overexpressed in prostate malignant glands, pointing it out as a putative biomarker for PCa. However, its localization and possible role in PCa cells remained unclear. In this study, we demonstrate that MCT2 localizes mainly at peroxisomes in PCa cells and is able...
Date: 2015
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Origin: RepositóriUM - Universidade do Minho