3 documents found, page 1 of 1
Trends of Exposure to Acrylamide as Measured by Urinary Biomarkers Levels withi...
Poteser, Michael; Laguzzi, Federica; Schettgen, Thomas; Vogel, Nina; Weber, Till; Murawski, Aline; Schmidt, Phillipp; Rüther, MariaAcrylamide, a substance potentially carcinogenic in humans, represents a very prevalent contaminant in food and is also contained in tobacco smoke. Occupational exposure to higher concentrations of acrylamide was shown to induce neurotoxicity in humans. To minimize related risks for public health, it is vital to obtain data on the actual level of exposure in differently affected segments of the population. To a...
A Tiered Approach for Assessing Individual and Combined Risk of Pyrethroids Usi...
Tarazona, Jose; Cattaneo, Irene; Niemann, Lars; Pedraza-Diaz, Susana; González-Caballero, MCarmen; Alba-Gonzalez, Mercedes de; Cañas, AnaPyrethroids are a major insecticide class, suitable for biomonitoring in humans. Due to similarities in structure and metabolic pathways, urinary metabolites are common to various active substances. A tiered approach is proposed for risk assessment. Tier I was a conservative screening for overall pyrethroid exposure, based on phenoxybenzoic acid metabolites. Subsequently, probabilistic approaches and more speci...
Time Trends of Acrylamide Exposure in Europe: Combined Analysis of Published Re...
Poteser, Michael; Laguzzi, Federica; Schettgen, Thomas; Vogel, Nina; Weber, Till; Zimmermann, Philipp; Hahn, Domenica; Kolossa-Gehring, MarikeMore than 20 years ago, acrylamide was added to the list of potential carcinogens found in many common dietary products and tobacco smoke. Consequently, human biomonitoring studies investigating exposure to acrylamide in the form of adducts in blood and metabolites in urine have been performed to obtain data on the actual burden in different populations of the world and in Europe. Recognizing the related health...