6 documents found, page 1 of 1
Diagnosis of Schistosoma mansoni infections : what are the choices in Brazilian...
Moraes, Vanessa Silva; Shollenberger, Lisa Marie; Siqueira, Liliane Maria Vidal; Borges, William de Castro; Harn, Donald A.The population of Brazil is currently characterised by many individuals harbouring low-intensity Schistosoma mansoni infections. The Kato-Katz technique is the diagnostic method recommended by the World Health Organization (WHO) to assess these infections, but this method is not sensitive enough in the context of low egg excretion. In this regard, potential alternatives are being employed to overcome the limits...
Serological proteomic screening and evaluation of a recombinant egg antigen for...
Moraes, Vanessa Silva; Shollenberger, Lisa Marie; Borges, William de Castro; Rabello, Ana Lúcia Teles; Harn, Donald A.Background: Despite decades of use of control programs, schistosomiasis remains a global public health problem. To further reduce prevalence and intensity of infection, or to achieve the goal of elimination in low-endemic areas, there needs to be better diagnostic tools to detect low-intensity infections in low-endemic areas in Brazil. The rationale for development of new diagnostic tools is that the current st...
Genetic homogeneity among Leishmania (Leishmania) infantum isolates from dog an...
Silva, Thais Almeida Marques da; Gomes, Luciana Inácia; Oliveira, Edward; Vital, Wendel Coura; Silva, Letícia de AzevedoBackground: Certain municipalities in the Belo Horizonte Metropolitan Area (BHMA), Minas Gerais, Brazil, have the highest human visceral leishmaniasis (VL) mortality rates in the country and also demonstrate high canine seropositivity. In Brazil, the etiologic agent of VL is Leishmania (Leishmania) infantum. The aim of this study was to evaluate the intraspecific genetic variability of parasites from humans and...
Ecto-nucleotidase activities of promastigotes from leishmania (Viannia) brazili...
Leite, Pauline Martins; Gomes, Rodrigo Saar; Figueiredo, Amanda Braga de; Serafim, Tiago Donatelli; Tafuri, Wagner Luiz; Gomes, Carolina CavaliériBackground: Leishmania (Viannia) braziliensis has been associated with a broad range of clinical manifestations ranging from a simple cutaneous ulcer to destructive mucosal lesions. Factors leading to this diversity of clinical presentations are not clear, but parasite factors have lately been recognized as important in determining disease progression. Given the fact that the activity of ecto-nucleotidases corr...
Multi-centric prospective evaluation of rk39 rapid test and direct agglutinatio...
Assis, Tália Santana Machado de; Braga, Alexandre Sérgio da Costa; Pedras, Mariana Junqueira; Oliveira, Edward José de; Barral, Aldina Maria PradoFundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Pesquisas Clínicas. Belo Horizonte, MG, Brasil; Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Pesquisas Clínicas. Belo Horizonte, MG, Brasil; Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Pesquisas Clínicas. Belo Horizonte, MG, Brasil; Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. L...
Stool examination and rectal biopsy in the diagnosis and evaluation of therapy ...
Rabello, Ana Lúcia Teles; Rocha, Roberto Sena; Oliveira, João Paulo Mendes de; Katz, Naftale; Lambertucci, José RobertoFrom each of a group of 217 adult males selected through enzyme-immunoassay or skin-test (Group A), six stool samples were examined by both the Lutz/Hoffman, Pons & Janer (Lutz/HPJ) and Kato/Katz methods. In addition, one oogram of the rectal mucosa was performed. By these methods, schistosomiasis was detected in 44.7%, 47.5% and 40.1% of the individuals respectively. To evaluate the methods in the assessment o...