3 documents found, page 1 of 1
Three Prime Repair Exonuclease 1 (TREX1) expression correlates with cervical ca...
Prati, Bruna; da Silva Abjaude, Walason; Termini, Lara; Morale, Mirian; Herbster, Suellen; Longatto, Adhemar; Nunes, Rafaella Almeida LimaAlterations in specific DNA damage repair mechanisms in the presence of human papillomavirus (HPV) infection have been described in different experimental models. However, the global effect of HPV on the expression of genes involved in these pathways has not been analyzed in detail. In the present study, we compared the expression profile of 135 genes involved in DNA damage repair among primary human keratinocy...
Strong SOD2 expression and HPV-16/18 positivity are independent events in cervi...
Rabelo-Santos, Silvia Helena; Termini, Lara; Boccardo, Enrique; Derchain, Sophie; Longatto, Adhemar; Andreoli, Maria Antonieta; Costa, Maria CecíliaIt is well known that persistent infection with high-risk HPV (hr-HPV), mostly HPV-16 and 18, is the main cause of cervical cancer development. Manganese superoxide dismutase (MnSOD or SOD2) are highly expressed in different neoplasia. The present study investigated SOD2 protein expression and the presence of hr-HPV types in 297 cervical samples including non-neoplastic tissue, cervical intraepithelial neoplasi...
Association of HPV infection and Chlamydia trachomatis seropositivity in cases ...
Rabelo-Santos, Silvia Helena