2 documents found, page 1 of 1
Emergence of Multidrug-Resistant Mycobacterium Tuberculosis of the Beijing Line...
Perdigão, J; Silva, C; Maltez, F; Machado, D; Miranda, A; Couto, I; Rabna, P; Florez de Sessions, P; Phelan, J; Pain, A; McNerney, R; Hibberd, MThe Beijing genotype comprises a highly disseminated strain type that is frequently associated with multidrug resistant (MDR) tuberculosis (TB) and increased transmissibility but, countries such as Portugal and Guinea-Bissau fall outside the regions phylogeographically associated with this specific genotype. Nevertheless, recent data shows that this genotype might be gradually emerging in these two countries as...
Experimental Evidence for Limited in vivo Virulence of Mycobacterium africanum
Cá, B; Fonseca, KL; Sousa, J; Maceiras, AR; Machado, D; Sanca, L; Rabna, P; Rodrigues, P; Viveiros, M; Saraiva, MTuberculosis remains a public health problem and a main cause of death to humans. Both Mycobacterium tuberculosis and Mycobacterium africanum cause tuberculosis. In contrast to M. tuberculosis, which is geographically spread, M. africanum is restricted to West Africa. Differences have also been found in the growth rate and type of disease caused by M. africanum, globally suggesting an attenuation of this bacter...