2 documents found, page 1 of 1
Causal pathways from enteropathogens to environmental enteropathy : findings fr...
Kosek, Margaret N.; Ahmed, Tahmeed; Bhutta, Zulfiquar; Caulfield, Laura; Guerrant, Richard; Houpt, Eric; Kang, Gagandeep; Lee, Gwenyth; Lima, AldoBackground: Environmentalenteropathy (EE),the adverseimpact offrequent and numerous entericinfections on the gut resulting in a state of persistent immune activation and altered permeability, has been proposed as a key determinant of growth failure in children in low- and middle-income populations. A theory-driven systems model to critically evaluate pathways through which enteropathogens, gut permeability, and...
Fecal markers of intestinal inflammation and permeability associated with the s...
Kosek, Rashidul; Babji, Sudhir; Shrestha, Sanjaya; Qureshi, Shahida; Amidou, Samie; Mduma, Estomih; Lee, Gwenyth; Yori, Pablo PeñataroEnteric infections are associated with linear growth failure in children. To quantify the association between intestinal inflammation and linear growth failure three commercially available enzyme-linked immunosorbent assays (neopterin [NEO], alpha-anti-trypsin [AAT], and myeloperoxidase [MPO]) were performed in a structured sampling of asymptomatic stool from children under longitudinal surveillance for diarrhe...