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Adenosine A(2A) receptor blockade reverts hippocampal stress-induced deficits a...

Batalha, V. L.; Pêgo, José M.; Fontinha, B. M.; Costenla, A. R.; Valadas, J. S.; Baqi, Y.; Radjainia, H.; Müller, C. E.; Sebastião, A. M.; Lopes, L. V.

Maternal separation (MS) is an early life stress model that induces permanent changes in the central nervous system, impairing hippocampal long-term potentiation (LTP) and spatial working memory. There are compelling evidences for a role of hippocampal adenosine A(2A) receptors in stress-induced modifications related to cognition, thus opening a potential window for therapeutic intervention. Here, we submitted ...


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