109 documents found, page 1 of 11
Exploring canine mast cell tumors: An investigation into demographic characteri...
Catarino, J; Pinello, K; Niza-Ribeiro, J; Santos, J; Payan-Carreira, R; Reis, J; Faísca, PMast cell tumors (MCT) are among the most common neoplasia in dogs, representing up to 21 % of skin tumors. However, etiology and risk factors for its development remain unclear. This study aimed to reduce this knowledge gap by comprehensively analyzing 905 MCT cases diagnosed in Portugal between 2019 and 2021, using descriptive and inferential analyses. Most tumors affected the skin, with 69.9 % and 21.2 % cla...
Biópsias Percutâneas Vertebrais – Experiência do nosso Centro
Gonçalves, J; Kuroedov, D; Pamplona, J; Fragata, I; Reis, JIntrodução: A biópsia percutânea vertebral tem substituído a biópsia cirúrgica aberta nos últimos 50 anos. A biópsia não-invasiva é mais custo-efetiva e tem menos complicações quando comparada com procedimentos abertos. Realizou-se uma revisão das biópsias percutâneas vertebrais realizadas no nosso centro para avaliar o yield diagnóstico e a segurança. Métodos: Analisou-se retrospetivamente 240 biópsias vertebr...
A Zero-Shot Learning Approach for Task Allocation Optimization in Cyber-Physica...
Pereira, E; Reis, J; Rosaldo J. F. Rossetti; Gil Manuel GonçalvesThe design and reorganization of Cyber-Physical Systems (CPSs) faces challenges due to the growing number of interconnected devices. To effectively handle disruptions and improve performance, rapid CPS design and development is crucial. The Task Resources Estimator and Allocation Optimizer (TREAO) addresses these challenges, by simulating and optimizing the tasks assignment to the CPS machines, recommending sui...
Lobar Lung Transplantation: A Single-Center 10-Year Experience
Cruz, Z; Neri, F; Roxo, M; Figueiredo, C; Moita, C; Costa, AR; Santos Silva, J; Reis, J; Maciel Barbosa, J; Calvinho, P; Semedo, LBackground: The shortage of donors for lung transplants is the main limitation of the preceding. Lobar transplantation is an alternative especially useful in patients with short stature and small thoracic cavities. The aim of this study was to perform a descriptive analysis of Portuguese patients who underwent lobar lung transplantation. Methods: A retrospective study was conducted, and patients submitted to lo...
Recomendações para o Diagnóstico e Tratamento da Infeção Não Complicada por Chl...
Andrade, P; Azevedo, J; Lisboa, C; Fernandes, C; Borrego, MJ; Borges-Costa, J; Reis, J; Santiago, F; Santos, A; Alves, JChlamydia trachomatis infection is the most prevalent sexually transmitted bacterial infection in the world. Being associated with a large number of asymptomatic carriers, the diagnosis is frequently challenging and requires appropriate laboratory testing. In Portugal, the incidence of the disease has been consistently increasing in recent years, meaning that special awareness is required for case identificatio...
Acute Treatment of Isolated Posterior Cerebral Artery Occlusion: Single Center ...
Cunha, B; Baptista, M; Pamplona, J; Carvalho, R; Perry da Câmara, C; Alves, M; Papoila, AL; Nunes, AP; Reis, J; Fragata, IBackground and objectives: Randomized trials for mechanical thrombectomy (MT) excluded patients with ischemic strokes due to isolated posterior cerebral artery occlusion (IPCAO), and there is no evidence for best acute treatment strategy in these patients. We aimed to assess the effectiveness and safety of MT in acute IPCAO. Methods: We retrospectively analyzed consecutive patients with acute stroke due to IPCA...
Dapagliflozin Impact on the Exercise Capacity of Non-Diabetic Heart Failure wit...
Reis, J; Teixeira, AR; Valentim Gonçalves, A; Ilhão Moreira, R; Pereira da Silva, T; Timóteo, AT; Cruz Ferreira, RBackground: Dapagliflozin has been shown to reduce morbidity and mortality in Heart Failure with reduced Ejection Fraction (HFrEF), but its impact on exercise capacity of non-diabetic HF outpatients is unknown. Methods: Adult non-diabetic HF patients with a left ventricular ejection fraction (LVEF) <50% were randomized 1:1 to receive dapagliflozin 10 mg or to continue with HF medication. Patients underwent a...
Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in Portugal
Carvalho Dias, M; Soares dos Reis, R; Santos, JV; Paiva Nunes, A; Ferreira, P; Maia, B; Fragata, I; Reis, J; Ramos Lopes, J; Cruz, L; Santo, GIntroduction: Since the publication of endovascular treatment trials and European Stroke Guidelines, Portugal has re-organized stroke healthcare. The nine centers performing endovascular treatment are not equally distributed within the country, which may lead to differential access to endovascular treatment. Our main aim was to perform a descriptive analysis of the main treatment metrics regarding endovascular ...
The adaptive immune landscape of the colorectal adenoma–carcinoma sequence
Freitas, JA; Gullo, I; Garcia, D; Miranda, S; Spaans, L; Pinho, L; Reis, J; Sousa, F; Baptista, M; Resende, C; Leitão, D; Durães, C; Costa, JLBackground. The tumor immune microenvironment exerts a pivotal influence in tumor initiation and progression. The aim of this study was to analyze the immune context of sporadic and familial adenomatous polyposis (FAP) lesions along the colorectal adenoma–carcinoma sequence (ACS). Methods. We analyzed immune cell counts (CD3+, CD4+, CD8+, Foxp3+, and CD57+), tumor mutation burden (TMB), MHC-I expression and PD-...
Liquid biopsy for disease monitoring in non-small cell lung cancer: The link be...
Fernandes, G; Sousa, C; Reis, J; Martins, N; Moura, CS; Guimarães, S; Justino, A; Pina, MJ; Magalhães, A; Queiroga, H; Marques, JA; Machado, JCIntroduction: Cell-free DNA (cfDNA) analysis offers a non-invasive method to identify sensitising and resistance mutations in advanced Non-Small Cell Lung Cancer (NSCLC) patients. Next-generation sequencing (NGS) of circulating free DNA (cfDNA) is a valuable tool for mutations detection and disease' s clonal monitoring. Material and methods: An amplicon-based targeted gene NGS panel was used to analyse 101 plas...