Made available in DSpace on 2018-11-26T17:34:48Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-01-01; Defects in angiogenesis and mitochondrial function in the placenta contribute to the pathogenesis of preeclampsia; however upstream regulators of these pathways are not known. It has been argued that placental hypoxia secondary to abnormal spiral artery remodeling may play a causal role in the angiogeni...