4 documents found, page 1 of 1
Plant-derived bioactives and oxidative stress-related disorders: A key trend to...
Salehi, B; Azzini, E; Zucca, P; Varoni, EM; Kumar, NVA; Dini, L; Panzarini, E; Rajkovic, J; Fokou, PVT; Peluso, I; Mishra, AP; Nigam, M; Rayess, YEPlants and their corresponding botanical preparations have been used for centuries due to their remarkable potential in both the treatment and prevention of oxidative stress-related disorders. Aging and aging-related diseases, like cardiovascular disease, cancer, diabetes, and neurodegenerative disorders, which have increased exponentially, are intrinsically related with redox imbalance and oxidative stress. Hu...
Lifestyle, Oxidative Stress, and Antioxidants: Back and Forth in the Pathophysi...
Sharifi-Rad, M; Anil Kumar, NV; Zucca, P; Varoni, EM; Dini, L; Panzarini, E; Rajkovic, J; Tsouh Fokou, PV; Azzini, E; Peluso, I; Prakash Mishra, AOxidative stress plays an essential role in the pathogenesis of chronic diseases such as cardiovascular diseases, diabetes, neurodegenerative diseases, and cancer. Long term exposure to increased levels of pro-oxidant factors can cause structural defects at a mitochondrial DNA level, as well as functional alteration of several enzymes and cellular structures leading to aberrations in gene expression. The modern...
Antiulcer agents: From plant extracts to phytochemicals in healing promotion
Sharifi-Rad, M; Fokou, P; Sharopov, F; Martorell, M; Ademiluyi, A; Rajkovic, J; Salehi, B; Martins, N; Iriti, M; Sharifi-Rad, JIn this narrative review, we have comprehensively reviewed the plant sources used as antiulcer agents. From traditional uses as herbal remedies, we have moved on to preclinical evidence, critically discussing the in vitro and in vivo studies focusing on plant extracts and even isolated phytochemicals with antiulcerogenic potential. A particular emphasis was also paid to Helicobacter pylori activity, with emphas...
Phytochemicals in Helicobacter pylori infections: What are we doing now?
Salehi, B; Sharopov, F; Martorell, M; Rajkovic, J; Ademiluyi, A; Sharifi-Rad, M; Fokou, P; Martins, N; Iriti, M; Sharifi-Rad, JIn this critical review, plant sources used as effective antibacterial agents against Helicobacter pylori infections are carefully described. The main intrinsic bioactive molecules, responsible for the observed effects are also underlined and their corresponding modes of action specifically highlighted. In addition to traditional uses as herbal remedies, in vitro and in vivo studies focusing on plant extracts a...