3 documents found, page 1 of 1
Lipid-based carriers for food ingredients delivery
Barroso, Livia; Viegas, Cláudia; Vieira, Joao; Ferreira-Pego, Cintia; Costa, Joyce; Fonte, PedroThe encapsulation in the food industry has gained relevant importance, mainly due to its contribution to solve food problems by reducing the loss of nutrients, prolong the shelf-life, and improve food quality and safety. The lipid-based delivery systems as microemulsions, liposomes, solid lipid nanoparticles and nanostructured lipid carriers are widely used to deliver food ingredients due to their ability to pr...
Intranasal drug delivery for treatment of Alzheimer's disease
Fonseca, Leonor Cancela; Lopes, Joao; Vieira, Joao; Viegas, Claudia; Oliveira, Claudia S.; Hartmann, Rafael P.; Fonte, PedroThe Alzheimer's disease is a neurodegenerative condition with severe consequences interfering with patient quality of life. It is characterized as a progressive and irreversible brain disorder hampering memory and thinking, affecting the capacity to perform daily tasks leading to physical and cognitive incapacitation. The conventional treatment occurs by the oral route, but it presents relevant drawbacks such a...
A brief overview of the oral delivery of insulin as an alternative to the paren...
Macedo, Ana; Filipe, Patricia; Thome, Natalia G.; Vieira, Joao; Oliveira, Carolina; Teodosio, Catarina; Ferreira, Raquel; Roque, Luis; Fonte, PedroDiabetes mellitus greatly affects the quality of life of patients and has a worldwide prevalence. Insulin is the most commonly used drug to treat diabetic patients and is usually administered through the subcutaneous route. However, this route of administration is ineffective due to the low concentration of insulin at the site of action. This route of administration causes discomfort to the patient and increase...