15 documents found, page 1 of 2
Intrahepatic Clear Cell Cholangiocarcinoma - An Uncommon Histologic Subtype: Ca...
Raimundo Fernandes, S; Baldaia, C; Pinto Marques, H; Tortosa, F; Ramalho, FClear-cell cholangiocarcinoma is a very uncommon variant of cholangiocarcinoma with a largely unknown natural history and prognosis. We report a case of a 51-year-old previously healthy woman presenting with a large liver nodule found on routine imaging. Needle biopsy of the lesion suggested a non-hepatocellular carcinoma. After extensive workup for other primary neoplasms, the patient underwent a partial hepat...
Acidentes de Serviço em Profissionais de Saúde: Identificação, Representações e...
Ramalho, FEste estudo de investigação teve subjacente a preocupação com a exposição microbiológica acidental nos profissionais de saúde, sabendo que os acidentes de trabalho por exposição microbiológica acidental constituem um dos principais riscos de transmissão ocupacional de infecções por contacto com sangue e outros fluidos corporais. Os agentes infecciosos mais frequentemente envolvidos neste tipo de acidente são os...
Prevenção e Controlo do Risco de Exposição Ocupacional à Tuberculose Pulmonar n...
Rodrigues, C; Ramalho, F; Xavier, MJ; Armeiro, S; Louro, F; Paes Duarte, AA Tuberculose é uma doença altamente contagiosa que atinge sobretudo idosos e pessoas com maior vulnerabilidade, embora afecte também a população activa, em particular os mais expostos como os profissionais de saúde. A sua transmissão é potenciada por factores demográficos, pela urbanização, pelo aparecimento de formas resistentes à medicação habitual e pela associação à infecção por VIH. Apresenta-se o modelo,...
Autoimmune cholangiopathy.
Marinho, R; Graça, H; Ramalho, F; Costa, A; Batista, A; De Moura, M CWe report two patients with mixed characteristics of primary biliary cirrhosis and autoimmune hepatitis. They are two female patients in their fifties (54 and 58 years-old) one of them with autoimmune phenomenon, rheumatoid arthritis and Sjögren syndrome. Both of them showed laboratory values of cholestasis and the liver biopsy revealed liver cirrhosis with significant lesions of the bile ducts. They were treat...
Apoptotic cell death does not parallel other indicators of liver damage in chro...
Rodrigues, CMP; Brites, D; Serejo, F; Costa, A; Ramalho, F; de Moura, MCThe mechanisms of hepatocyte damage and the events that lead to high rates of chronic liver disease in hepatitis C virus (HCV) infection remain unclear. Recent in vitro studies have suggested that the HCV core protein may disrupt specific signalling pathw
Vaccine against hepatitis B. Eight years of experience.
Marinho, R T; Pedro, M; Ramalho, F; Velosa, J; De Moura, M CHepatitis B virus infection is one of the world's major health problems and health care workers are especially at risk, leading to the need for a high priority vaccination program. Such a program was begun in 1989 in S. Maria Hospital and included all hospital personnel and students of the Faculty of Medicine. The screening included 2360 health care workers and 1153 students. Fifty-five percent of hospital heal...
A structural analysis of the entrance exams for specialist interns from 1994 to...
Morgado, V; da Costa, A G; Correia, A; Pereira, A; Pinho, A C; de Araújo, A T; Ramalho, F; Gouveia, J; Quininha, J; Nogueira, J B; Romãozinho, J MIn order to obtain specialist training in Portugal, doctors must pass a multiple-choice examination. The aim of this article is to present a structural and mathematical analysis of the examinations in the last three years. We based our work on the calculation of reliability coefficient of the examinations, and the difficulty and discrimination index of the questions and the examinations as a whole. A detailed a...
Infection with hepatitis C virus in porphyria cutanea tarda.
Lima, J; Serejo, F; Gloria, H; Ramalho, F; Moura, M CThe authors make a literature review on hepatitis C virus infection in porphyria cutanea tarda, illustrated by one clinical case. They also present some considerations about pathophysiologic mechanisms involved in this association.; The authors make a literature review on hepatitis C virus infection in porphyria cutanea tarda, illustrated by one clinical case. They also present some considerations about pathoph...
Prevalence of chronic hepatic disease in Portugal. Apropos of a review carried ...
Valente, A I; Almeida, A; Gouveia, A; Serejo, F; Ramalho, F; Baptista, A; Saragoça, A; Moura, M CThe chronic elevation of Aminotransferases is one of the most frequent indications for percutaneous Liver Biopsy (LB). From a retrospective study of LB performed in the Hepatology liver Unit of Santa Maria Hospital, between 1989 and 1993, we correlated the histologic diagnosis with the etiology of liver disease, sex, age and the Aspartate aminotransferase/Alanine aminotransferase (AST/ALT) and Gama-Glutamyl tra...
The intrahepatic expression of the hepatitis B virus in chronic delta hepatitis.
Ramalho, F; Velosa, J; Costa, A; Baptista, A; de Moura, M CIn order to evaluate the interference of hepatitis delta virus (HDV) in hepatitis B viral particle (HBsAg, HBcAg) expression in the liver of chronic HDV patients, 39 and 81 liver biopsies of HBsAg carriers seropositive for anti-HDV and anti-HDV negative controls, respectively, were studied. HBcAg was positive in 16.7% of the HBeAg-positive patients with HDAg in the liver and in 91,4% of controls. In contrast, i...