3 documents found, page 1 of 1
New Red-Shifted 4-Styrylcoumarin Derivatives as Potential Fluorescent Labels fo...
Eustáquio, R.; Ramalho, J.P.P.; Caldeira, A.T.; Pereira, A.Important scientific areas, such as cellular biology, medicine, pharmacy, and environmental sciences, are dependent on very sensitive analytical techniques to track and detect biomolecules. In this work, we develop a simple, low-cost and effective synthetic strategy to produce new red-shifted 4-styrylcoumarin derivatives as promising inexpensive fluorescent labels for biomolecules. The extension of the delocali...
Development of new 2-piperidinium-4- styrylcoumarin derivatives with large Stok...
Eustáquio, R.; Ramalho, J.P.P.; Caldeira, A.T.; Pereira, A.A series of novel 2-piperidinium-4-styrylcoumarin derivatives, with large Stokes shifts and high fluorescence quantum yields, were synthesized using an efficient and low-cost synthetic strategy as potential fluorescent labels for biomolecules. Density functional theory and time-dependent density functional theory calculations were performed in order to rationalize the observed photophysical properties.; The stu...
6.4. New Red-Shifted 4-Styryl Coumarins as Potential Fluorescent Labels for Bio...
Eustáquio, R.; Ramalho, J.P.P.; Caldeira, A.T.; Pereira, A.Cellular biology, medicine, pharmacy, environmental sciences and other important scientific areas require highly sensitive analytical techniques to track and detect nucleic acids, oligonucleotides, antibodies, amino acids, proteins, lipids, carbohydrates, and other biomolecules. Of all sensitive analytical techniques, fluorescent labeling presents numerous advantages as it allows the use of small sample quantit...