4 documents found, page 1 of 1
Cost-effectiveness of Xpert®MTB/RIF in the diagnosis of tuberculosis: pragmatic...
Silva,Suely Conceição Alves da; Vater,Maria Claudia; Ramalho,Daniela Maria de Paula; Almeida,Isabela Neves de; Miranda,Silvana Spíndola deAbstract INTRODUCTION: The intensification of research and innovation with the creation of networks of rapid and effective molecular tests as strategies for the end of tuberculosis are essential to avoid late diagnosis and for the eradication of the disease. We aimed to evaluate the cost-effectiveness of Xpert®MTB/RIF (Xpert) in the diagnosis of drug-resistant tuberculosis in reference units, in scenarios with ...
Association between serum selenium level and conversion of bacteriological test...
Moraes,Milena Lima de; Ramalho,Daniela Maria de Paula; Delogo,Karina Neves; Miranda,Pryscila Fernandes Campino; Mesquita,Eliene Denites DuarteObjective: To determine whether serum selenium levels are associated with the conversion of bacteriological tests in patients diagnosed with active pulmonary tuberculosis after eight weeks of standard treatment. Methods: We evaluated 35 healthy male controls and 35 male patients with pulmonary tuberculosis, the latter being evaluated at baseline, as well as at 30 and 60 days of antituberculosis treatment. For a...
Inflammatory and immunogenetic markers in correlation with pulmonary tuberculosis
Muller,Beatriz Lima Alezio; Ramalho,Daniela Maria de Paula; Santos,Paula Fernanda Gonçalves dos; Mesquita,Eliene Denites Duarte; Kritski,Afranio LineuOBJECTIVE: To describe serum levels of the cytokines IL-10, TNF-α, and IFN-γ, as well as polymorphisms in the genes involved in their transcription, and their association with markers of the acute inflammatory response in patients with pulmonary tuberculosis.METHODS: This was a descriptive, longitudinal study involving 81 patients with pulmonary tuberculosis treated at two referral hospitals. We collected data ...
Termo de consentimento e análise de material biológico armazenado
Duque,Cristiano Guedes; Ramalho,Daniela Maria de Paula; Casali-da-Rocha,José CláudioOBJETIVO: Relatar uma experiência envolvendo a obtenção de termo de consentimento livre e esclarecido (TCLE) para estudo retrospectivo realizado no Instituto Nacional de Câncer (INCA). O mesmo envolvia a revisão de prontuários e a análise de blocos de parafina de pacientes com câncer de cólon operados entre 2000 e 2004. Respeitando a resolução 196/96 do Conselho Nacional de Saúde e a determinação do Comitê de É...