Funding Information: G.D. and N.F.L. contributed equally to this work and share co-first authorship. The authors acknowledge funding from the Funda\u00E7\u00E3o para a Ci\u00EAncia e a Tecnologia/ Minist\u00E9rio da Ci\u00EAncia, Tecnologia e Ensino Superior (FCT/MCTES, Portugal) through national funds to iNOVA4Health (UIDB/04462/2020 and UIDP/04462/2020), the Associate Laboratory LS4FUTURE (LA/P/0087/2020), th...