3 documents found, page 1 of 1
A general deep hybrid model for bioreactor systems
Pinto, José; Mestre, Mykaella; Ramos, J.; Costa, Rafael S.; Striedner, Gerald; Oliveira, RuiJP acknowledges PhD grant SFRD/BD14610472019, This work has received funding from the European Union's Horizon 2020 research and innovation program under grant agreement no 101000733 (PROMICON).; Numerous studies have reported the use of hybrid semiparametric systems that combine shallow neural networks with First Principles for bioprocess modeling. Here we revisit the general bioreactor hybrid model and introd...
Portuguese recommendations for the use of biological therapies in patients with...
Duarte, Cátia; Sousa-Neves, J.; Águeda, A.; Ribeiro, P.; Daniel, A.; Eugénio, G.; Silvério Serra, Sofia; Araújo, F.; Barcelos, A.; Filipe, B.Objective: To update the recommendations for the treatment of rheumatoid arthritis (RA) with biological therapies, endorsed by the Portuguese Society of Rheu -matology (SPR). Methods: These treatment recommendations were formulated by Portuguese rheumatologists based on litera -ture evidence and consensus opinion. At a national meeting the 11 recommendations were discussed and updated. The document resulting fr...
Portuguese recommendations for the use of methotrexate in rheumatic diseases - ...
Duarte, Ana Catarina; Santos-Faria, D.; Gonçalves, M. J.; Sepriano, Alexandre; Mourão, A. F.; Duarte, C.; Neves, J. S.; Águeda, A. F.; Ribeiro, P. A.Background: Methotrexate (MTX) is the first-line drug in the treatment of rheumatoid arthritis (RA) and the most commonly prescribed disease modifying antirheumatic drug. Moreover, it is also used as an adjuvant drug in patients under biologic therapies, enhancing the efficacy of biologic agents. Objectives: To review the literature and update the Portuguese recommendations for the use of MTX in rheumatic disea...