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Gla-rich protein is involved in the cross-talk between calcification and inflam...
Cavaco, Sofia; S B Viegas, Carla; Rafael, Marta S.; Ramos, Acacio; Magalhes, Joana; Blanco, Francisco J.; Vermeer, Cees; Simes, DOsteoarthritis (OA) is a whole-joint disease characterized by articular cartilage loss, tissue inflammation, abnormal bone formation and extracellular matrix (ECM) mineralization. Disease-modifying treatments are not yet available and a better understanding of osteoarthritis pathophysiology should lead to the discovery of more effective treatments. Gla-rich protein (GRP) has been proposed to act as a mineraliza...
Date: 2016
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Origin: Sapientia - Universidade do Algarve