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The Temporal Trends of Mortality Due to Tuberculosis in Brazil: Tracing the Cor...

Tavares, Reginaldo; Gomes, Dulce; Berra, Thaís Zamboni; Alves, Yan; Ramos, Antônio; Popolin, Marcela; Abade, André; Zini, Natália; Tártaro, Ariela

An ecological study of TB deaths recorded in the Mortality Information System (SIM) from 2012 to 2022 was conducted. Trends and percentage changes in the mortality were estimated. A Bayesian Structural Time Series model combined with an Autoregressive Integrated Moving Average model was used to assess the pandemic’s effect on TB.


Operational indicators for pulmonary tuberculosis diagnosis in people living wi...

Faria, Mariana; Andrade, Rubia; Leite, Karina; Bonfim, Rafaele; Valênça, Ana; Ramos, Antônio; Berra, Thais; Arcêncio, Ricardo; Netto, Antônio Ruffino

Tuberculosis (TB) in people living with HIV (PLHIV) is usually paucibacillary and the smear microscopy has limitations and may lead to high proportions of non-confirmed pulmonary tuberculosis (NC-PTB). Despite culture being the reference method, it usually takes 6 to 8 weeks to produce the results. This study aimed to analyze the effect of a rapid molecular test (Xpert) in the confirmatory rate of PTB among PLH...


Evolução temporal e distribuição espacial da hanseníase em município de baixa e...

Ramos, Antônio; Martoreli Júnior, José Francisco; Zamboni Berra, Thaís; Mathias Alves, Yan; Pestana Barbosa, Tatiana; Rolim Scholze, Alessandro

Analisar a distribuição espacial e temporal da hanseníase em cenário de baixa endemicidade no estado de São Paulo, Brasil. Estudo ecológico, sobre casos de hanseníase notificados no município de Ribeirão Preto, entre 2006 e 2016. A tendência temporal da taxa de detecção de hanseníase foi verificada mediante decomposição de séries temporais, e identificadas as áreas de alta e de baixa ocorrência da doença utiliz...


Impact of COVID-19 on Tuberculosis Indicators in Brazil: A Time Series and Spat...

Zamboni Berra, Thaís; Ramos, Antônio; Alves, Yan; Tavares, Reginaldo; Fehr Tartaro, Ariela; Nascimento, Murilo; Moura, Heriederson; Delpino, Filipe

We aimed to visualize and classify the time series of COVID-19, tuberculosis (TB) notification, and TB outcomes (cure, treatment abandonment, and death), verify the impact of the new coronavirus pandemic on these indices in Brazil, and verify the presence of spatial autocorrelation between COVID-19 and TB. Methods: This was an ecological time series study that considered TB and COVID-19 cases. Seasonal Trend De...


Inequality of gender, age and disabilities due to leprosy and trends in a hyper...

Martoreli Júnior, Francisco; Ramos, Antônio; Alves, Josilene; Almeida Crispim, Juliane; Seles Alves, Luana; Zamboni Berra, Thaís; Barbosa, Tatiana

In the 2019 report, Brazil had a detection rate of 13.23 per 100.000 inhabitants far from the goal of less than 1 leprosy (Hansen’s Disease) case per 10,000 inhabitants describe by the World Health Organization. The present study aimed to investigate the epidemiological situation of leprosy and its trend between 2008 and 2018 in a hyperendemic metropolis in the Central-West region of Brazil. A total of 9.739 le...


Tuberculosis forecasting and temporal trends by sex and age in a high endemic c...

Andrade, Hamilton; Gomes, Dulce; Ramos, Antônio; Arroyo, Luiz; Santos Neto, Marcelino; Palha, Pedro; Fiorati, Regina; Fronteira, Inês; Monroe, Aline

The aim of this study was to describe the temporal trend of tuberculosis cases according to sex and age group and evidence the level of disease before the Covid-19 pandemic in a TB high endemic city


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