22 documents found, page 1 of 3
The Dystrophin-Dystroglycan complex ensures cytokinesis efficiency in Drosophil...
Gonçalves, M; Lopes, C; Alégot, H; Osswald, M; Bosveld, F; Ramos, C; Richard, G; Bellaiche, Y; Mirouse, V; Morais-de-Sá, ECytokinesis physically separates daughter cells at the end of cell division. This step is particularly challenging for epithelial cells, which are connected to their neighbors and to the extracellular matrix by transmembrane protein complexes. To systematically evaluate the impact of the cell adhesion machinery on epithelial cytokinesis efficiency, we performed an RNAi-based modifier screen in the Drosophila fo...
Developing and Validating High-Value Patient Digital Follow-Up Services: a Pilo...
Londral, A; Azevedo, S; Dias, P; Ramos, C; Santos, J; Martins, F; Silva, R; Semedo, H; Vital, C; Gualdino, A; Falcão, J; Lapão, LV; Coelho, PBackground: The existing digital healthcare solutions demand a service development approach that assesses needs, experience, and outcomes, to develop high-value digital healthcare services. The objective of this study was to develop a digital transformation of the patients' follow-up service after cardiac surgery, based on a remote patient monitoring service that would respond to the real context challenges. Me...
Brain MRI in the Decision for Liver Transplantation in Pediatric Neurological W...
Pinto, C; Malaquias, MJ; Miranda, HP; Temudo, T; Silva, E; Ramos, C; Magalhaes, MBackground Neurological Wilson's disease (WD) presentation in the pediatric population is rare, and liver transplantation (LT) in these patients remains controversial. The aim of the present study was to assess the role of brain magnetic resonance imaging (MRI) in predicting reversion of brain lesions and neurological outcomes in pediatric WD patients after LT. Methods Patients with confirmed WD (Leipzig score ...
Quality of undisturbed samples of cohesionless soils collected with advanced pr...
Ramos, C; Molina Gómez, F; Cristiana Ferreira; da Fonseca, AVOver the past decade, soil-sampling techniques have evolved in order to reduce friction in the interface between the sampler and the soil, minimizing soil disturbance and collecting high-quality samples for laboratory characterisation. Under research projects focused on liquefaction studies in Portugal (LIQ2PROEARTH) and in Europe (LIQUEFACT), an experimental site was implemented in the areas of Benavente and V...
FOREWORD: SPECIAL ISSUE "EURO 2019: GAMES IN ECONOMICS, FINANCE AND BIOLOGY"
Martn Herran, G; Mazalov, V; Petrosyan, L; Bruno M P M Oliveira; Ramos, C; Weber, GW; Zenkevich, N; Daniele, P; Fulga, C
Acquired hepatocerebral degeneration and hepatic encephalopathy: one or two ent...
Malaquias, MJ; Pinto, CM; Ramos, C; Ferreira, S; Gandara, J; Almeida, A; Cavaco, S; Miranda, HP; Magalhães, MBackground and purpose: Acquired hepatocerebral degeneration (AHD) and hepatic encephalopathy (HE) are neurological complications of chronic liver disease (CLD) with portosystemic shunt. While HE is common, AHD is a rare entity, and the clinical imaging relationships observed in small series lack validation in large patient cohorts. The aim of this study was to characterize a cohort of AHD patients and to explo...
Cytotoxic and Genotoxic Effects of Environmental Relevant Concentrations of Bis...
Ramos, C; Ladeira, C; Zeferino, S; Dias, A; Faria, I; Cristovam, E; Gomes, M; Ribeiro, EBisphenol A (BPA) is one of the most widely utilized endocrine disruptors to which humans are exposed, particularity through ingestion. BPA is an aneugenic compound with a putative association to tumorigenesis. Although extensively studied in estrogen responsive cells, information regarding its effects on cells from the upper gastrointestinal tract exposed to free/active forms of BPA is still scarce. Similarly,...
Gordon Holmes syndrome due to compound heterozygosity of two new PNPLA6 variant...
Salgado, P; Carvalho, R; Brandão, AF; Jorge, P; Ramos, C; Dias, D; Alonso, I; Magalhães, MBackground: Gordon Holmes syndrome (GHS), characterized by cerebellar ataxia and hypogonadotropic hypogonadism (HH), has been related to recessive mutations in PNPLA6 gene. Aims of the study: Describe one Portuguese family with GHS due to compound heterozygosity of two new PNPLA6 variants. Methods: Report on the clinical presentation, diagnostic and genetic workup to reach GHS diagnosis. Results: The index case...
Changes of Soluble CD40 Ligand in the Progression of Acute Myocardial Infarctio...
Napoleão, P; Monteiro, MC; Cabral, L; Criado, MB; Ramos, C; Selas, M; Viegas-Crespo, AM; Saldanha, C; Mota Carmo, M; Cruz Ferreira, R; Pinheiro, TReported in vitro data implicated soluble CD40 ligand (sCD40L) in endothelial dysfunction and angiogenesis. However, whether sCD40L could exert that influence in endothelial dysfunction and angiogenesis after injury in acute myocardial infarction (AMI) patients remains unclear. In the present study, we evaluated the association of sCD40L with markers of platelet activation, endothelial, and vascular function du...
APPLICATION OF A RECENTLY DEVELOPED GEOTECHNICAL CARBON CALCULATOR
Sara Rios; Cristelo, N; da Fonseca, AV; Rosa, I; Ramos, CRecent research regarding soil stabilization has been increasingly concerned with environmental perfoimance. The present paper applies the newly developed CO2(eq) geotechnical calculator, created by the European Federation of Foundation Contractors and the The Deep Foundations Institute, to assess the behavior of three different binders used in the construction of cutter-soil mixing columns, which foamed an emb...