21 documents found, page 1 of 3

Toward a platform for the treatment of burns: An assessment of nanoemulsions vs...

Curcumin is a highly promising substance for treating burns, owing to its anti-inflammatory, antioxidant, antimicrobial, and wound-healing properties. However, its therapeutic use is restricted due to its hydrophobic nature and low bioavailability. This study was conducted to address these limitations; it developed and tested two types of lipid nanocarriers, namely nanoemulsions (NE-CUR) and nanostructured lipi...

Behavioral changes of the population in the city of Rio Grande (RS) facing the ...

Classified as a pandemic by the World Health Organization, COVID-19 has become a protagonist in public health demands around the world. In Brazil, the second country with the most deaths, Rio Grande do Sul is the sixth state most affected by COVID-19. Therefore, an online research was conducted with the residents of the city of Rio Grande, in the south of the state, to assess the impact of the pandemic on the l...

Whole-genome sequencing as a tool for studying the microevolution of drug-resis...

Treatment of drug-resistant tuberculosis requires extended use of more toxic and less effective drugs and may result in retreatment cases due to failure, abandonment or disease recurrence. It is therefore important to understand the evolutionary process of drug resistance in Mycobacterium tuberculosis. We here in describe the microevolution of drug resistance in serial isolates from six previously treated patie...

Avaliação das atividades antifúngica, antimicobacteriana e larvicida de Duroia ...

Triterpenes and the antimycobacterial activity of duroia macrophylla huber (Rub...

Duroia macrophylla popularly known as "cabeça-de-urubú, " "apuruí," or "puruí-grande-da-mata" occurs in the Amazon Forest. Its leaves and branches were collected twice and extracted with dichloromethane and methanol. All extracts were subjected to phytochemical investigation and terpenes and flavonoids were found in all dichloromethane and methanol extracts, respectively. Methanol extracts from both branches (1...

The interplay between mutations in cagA, 23S rRNA, gyrA and drug resistance in ...

In this study, we evaluated the mutations of Helicobacter pylori associated with resistance to clarithromycin and levofloxacin. Furthermore, based on the proposed interaction between antimicrobial resistance and pathogenicity, we correlated the mutation profiles of the strains with the presence of the pathogenicity gene cagA. We analyzed 80 gastric biopsy specimens from H. pylori-infected patients for point mut...

Assessment of Ibicella lutea for antibacterial agent front Staphylococcus aureus

Justificative and Objectives: the study aimed the assessment of the antibacterial activity of crude extracts and fractions of Ibicella lutea, front Staphylococcus aureus, thecombination of these compounds and cytotoxic activity. Methods: was used for antibacterial activity the Microdilution Test Broth, and performed the Checkerboard Test. The extracts showed antibacterial activity were submitted to the citotoxi...

Antimicrobial activity of Ilex paraguariensis extracts

JUSTIFICATIVA E OBJETIVO: A Ilex paraguariensis St. Hilaire é conhecida popularmente como mate ou erva-mate, consumida popularmente no sul do Brasil, Paraguai e Argentina. Estudos têm evidenciado atividades bioativas da Ilex paraguariensis, como a atividade antioxidante, antinflamatória, diurética, digestiva, cicatricial e estimulante, conferindo um potencial terapêutico à mesma. Tais atividades bioativas da Il...

Factors associated with ciprofloxacin and Levofloxacin resistance in Gram-Negat...

Background and Objectives: Fluoroquinolones represent a class of amtimicrobials which isfrequently prescribed for the treatment of urinary tract infections (UTIs) of both hospital and community origin. This study aims, to determine the frequency and the factors associated with resistance to ciprofloxacin and levofloxacin in gram-negative bacilli isolated from patients with UTIs treated in a hospital in southern...

Antimycobacterial and cytotoxicity activity of microcystins. Journal of venomou...

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