Made available in DSpace on 2022-04-29T08:36:37Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-12-01; Cryptococcosis is associated with high rates of morbidity and mortality, especially in AIDS patients. Its treatment is carried out by combining amphotericin B and azoles or flucytosine, which causes unavoidable toxicity issues in the host. Thus, the urgency in obtaining new antifungals drives the search...
Made available in DSpace on 2020-12-12T01:51:42Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-12-06; Invasive fungal infections, such as cryptococcosis and paracoccidioidomycosis are associated with significant rates of morbidity and mortality. Cryptococcosis, caused by Cryptococcus neoformans, is distributed worldwide and has received much attention as a common complication in patients with HIV. Invas...