Despite the fact that on December 10, 2023 were celebrated 75 years since the Universal Declaration of Human Rights, we continue to witness a daily trampling of the most elementary rights of citizens in today's world. [...]
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Triple-negative breast cancer (TNBC) is one of the most aggressive forms of breast cancer and constitutes 10-20% of all breast cancer cases. Even though platinum-based drugs such as cisplatin and carboplatin are effective in TNBC patients, their toxicity and development of cancer drug resistance often hamper their clinical use. Hence, novel drug entities with improved tolerability and selectivity profiles, as w...
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This systematic literature review was based on the research question: “What are the potentials and limitations of nature education in early childhood settings?”, with the purpose of analyzing and systematizing, on the one hand, the benefits of these educational experiences, in terms of health, development and environmental awareness of children, and, on the other hand, the obstacles and challenges to practices,...
Objective: To analyze changes in performance indicators five years after Portugal joined the Stent for Life (SFL) initiative. Methods: National surveys were carried out annually over one-month periods designated as study Time Points between 2011 (Time Zero) and 2016 (Time Five). In this study, 1340 consecutive patients with suspected ST-elevation myocardial infarction (STEMI) who underwent coronary angiography,...
Since its detection in December of 2020, the SARS-CoV2 lineage P.1, descendent of B.1.1.28 lineage, has been identified in several places in Brazil and abroad. This Variant of Concern was considered highly prevalent in Northern Brazil and now is rapidly widening its geographical range. Here, we present epidemiological and genomic information of the first case of P1 lineage in Rio Grande do Sul state, in a patie...
Os textos apresentados neste volume constituem reflexões críticas que têm por base algumas técnicas de análise de dados de investigação qualitativa (Análise Temática, Análise de Discurso, Análise de Conteúdo, Análise Factorial e Análise de Variância). Os organizadores e autores não olham para estas reflexões como algo fechado, mas como ponto de partida… Os capítulos que se apresentam nesta publicação resultam d...
O presente artigo tem como objetivos i) aprofundar conhecimento, ii) problematizar e fomentar o levantamento de questões sobre a técnica de análise de conteúdo, na sua dimensão conceptual e prática. De facto, pretende-se fomentar a sua utilização e aplicação por parte do investigador, de forma consciente, assertiva e adequada. Por conseguinte, através de um posicionamento crítico perante o cruzamento de perspet...
Introduction: Hospitalization is an opportunity to assess in astructured way the vulnerability of elderly patients. The authorspresent the AGE project for Geriatric Structured Assessment,developed in an Internal Medicine Service of PortoHospital Center.Methods: The AGE project was characterized by the applicationof a vulnerability screening scale (VES-13) to allhospitalized elderly patients followed by a qualit...