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Quantitative assessment of myocardial fibrosis by digital image analysis: an ad...

Abecasis, João; Cortez-Dias, Nuno; Pinto, Daniel Gomes; Lopes, Pedro; Madeira, Márcio; Ramos, Sancia; Gil, Victor; Cardim, Nuno; Félix, Ana

Aims: Myocardial fibrosis (MF) is a common pathological process in a wide range of cardiovascular diseases. Its quantity has diagnostic and prognostic relevance. We aimed to assess if the complementary use of an automated artificial intelligence software might improve the precision of the pathologist´s quantification of MF on endomyocardial biopsies (EMB). Methods and results: Intraoperative EMB samples from 30...


Quantitative assessment of myocardial fibrosis by digital image analysis: an ad...

Abecasis, João; Cortez-Dias, Nuno; Pinto, Daniel Gomes; Lopes, Pedro; Madeira, Márcio; Ramos, Sancia; Gil, Victor; Cardim, Nuno; Félix, Ana

AIMS: Myocardial fibrosis (MF) is a common pathological process in a wide range of cardiovascular diseases. Its quantity has diagnostic and prognostic relevance. We aimed to assess if the complementary use of an automated artificial intelligence software might improve the precision of the pathologist´s quantification of MF on endomyocardial biopsies (EMB). Methods and results: Intraoperative EMB samples from 30...


DMBT1 is frequently downregulated in well-differentiated gastric carcinoma but ...

Conde, Ana R.; Martins, Ana P.; Brito, Miguel; Manuel, Armandina; Ramos, Sancia; Malta-Vacas, Joana; Renner, Marcus; Poustka, Annemarie

Well-differentiated gastric carcinomas are considered to represent a distinct entity emerging via specific molecular changes different from those found in other gastric carcinoma types. The gene deleted in malignant brain tumours 1 (DMBT1) at 10q25.3-q26.1 codes for a protein presumably involved in cell differentiation and protection and has been proposed as a candidate tumour suppressor for brain and epithelia...


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