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Lymphogranuloma venereum: a retrospective analysis of an emerging sexually tran...

Neves, José Miguel; Ramos Pinheiro, Rita; Côrte-Real, Rita; Borrego, Maria José; Rodrigues, Ana; Fernandes, Cândida

Background: Lymphogranuloma venereum (LGV) is a sexual transmitted infection (STI), currently endemic within the population of men who have sex with men (MSM) of Western Countries. L2B variant has been reported as the predominant strain in the current LGV epidemics, although a shift towards L2-434 has been observed in some European countries. Objectives: To evaluate and characterize the population with LGV infe...


Topical Immunomodulation with Diphenlycyclopropenone for Alopecia Areata

Borges, Ana Sofia; Brasileiro, Ana; Ramos Pinheiro, Rita; Lencastre, André

Introduction: Topical immunotherapy with diphenylcyclopropenone is a treatment option for patients with refractory or extensive alopecia areata. The aim of this study was to evaluate the clinical efficacy and tolerability of diphenylcyclopropenone therapy, in patients with alopecia areata, and identify possible prognostic factors that predict response to treatment. Methods: We conducted a retrospective study th...


Case of Permanent Chemotherapy-Induced Alopecia with Response to Topical Minoxidil

Matos Pires, Eugénia; Ramos Pinheiro, Rita; Lencastre, André

Permanent chemotherapy-induced alopecia is uncommon and has primarily been reported after high-dose busulfan chemotherapy in bone marrow transplant patients. Nevertheless, cases of PCIA, after taxane chemotherapy protocols for breast cancer, have been recently described. Despite the impact on patients’ quality of life, no consistently effective treatment has been previously described for taxane-associated perma...


Auto-immune Photodermatoses Part I – Pathogenesis and Diagnosis

Coelho de Sousa, Virginia; Ramos Pinheiro, Rita; Rocha Páris, Filipa; Apetato, Margarida; Marques Pinto, Gabriela

The autoimmune photodermatoses are a group of heterogeneous idiopathic dermatoses physiopathologically characterized by underexplored immune mechanisms, usually involving an immune reaction against an unknown antigen. This group includes five different clinical entities – polymorphous light eruption, actinic prurigo, hydroa vacciniforme, chronic actinic dermatitis, solar urticaria - some potentially severe with...


Autoimmune Photodermatoses Part II - Clinical Manifestations and Treatment

Ramos Pinheiro, Rita; Coelho de Sousa, Virgínia; Rocha Páris, Filipa; Apetato, Margarida; Marques Pinto, Gabriela

The autoimmune photodermatoses are a group of heterogeneous idiopathic dermatoses including five different clinical entities some potentially severe with great impact in patients’ quality of life. General photoprotection measures are sufficient for the treatment of patients with mild forms of disease. In severe disease the therapeutic options are still limited, reflecting the ill-defined physiopathological mech...


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