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Rapid and efficient synthesis of α(1 – 2) mannobiosides.

Reina, José Juan; Maio, Antonio Di; Ramos Soriano, Javier; Figueiredo, Rute Cunha; Rojo Marcos, Francisco Javier

α(1,2) mannobiosides with different substituents at the reducing end have been synthesized by a common strategy using benzoyls as the permanent protecting groups and an acetyl as the orthogonal protecting group at position C2 of the glycosyl acceptor. The new synthetic strategy has been performed remarkably reducing the number of purification steps, the time of synthesis (less than 72 hours) and improving the o...

Date: 2016   |   Origin: Oasisbr

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