5 documents found, page 1 of 1
Full physicochemical and biocompatibility characterization of a supercritical C...
Souto-Lopes, M; Grenho, L; Manrique, YA; Dias, MM; Fernandes, MH; Monteiro, FJ; Salgado, CDespite bone's innate self-renewal capability, some periodontal pathologic and traumatic defects' size inhibits full spontaneous regeneration. This current research characterized a 3D porous biodegradable nano-hydroxyapatite/chitosan (nHAp/CS, 70/30) scaffold for periodontal bone regeneration, which preparation method includes the final solvent extraction and sterilization through supercritical CO2 (scCO2). Mic...
45S5 bioglass-derived glass-ceramic scaffolds containing niobium obtained by ge...
Siqueira, L; Grenho, L; Fernandes, MH; Monteiro, FJ; Trichês, ESScaffolds of bioglass derived from BG45S5 (45 wt% SiO2, 24.5 wt% CaO, 24.5 wt% Na2O and 6 wt% P2O5) containing 10 wt% niobium were prepared by gelcasting method. The scaffolds presented a 3D porous structure with interconnected and spherical pores (pore size range 100 µm to 500 µm) and high porosity (89%), similar to trabecular architecture of spongy bone. The compressive strength was 0.18 ± 0.03 MPa which is a...
Nano-hydroxyapatite in oral care cosmetics: characterization and cytotoxicity a...
Coelho, CC; Grenho, L; Gomes, P; Quadros, P; Fernandes, MNano-hydroxyapatite has been used as an oral care ingredient, being incorporated in several products for the treatment of dental hypersensitivity and enamel remineralisation. Despite its promising results, regulatory and safety concerns have been discussed and questioned by the European Scientific Committee on Consumer Safety (SCCS) regarding the usage of hydroxyapatite nanoparticles in oral care products. In t...
Influence of PLLA/PCL/HA scaffold fiber orientation on mechanical properties an...
de, Siqueira, L; Ribeiro, N; Paredes, MBA; Grenho, L; Cunha-Reis, C; Trichês, ES; Fernandes, MH; Sousa, SR; Monteiro, FJScaffolds based on aligned and non-aligned poly (L-lactic acid) (PLLA)/polycaprolactone (PCL) fibers obtained by electrospinning, associated to electrosprayed hydroxyapatite (HA) for tissue engineering applications were developed and their performance was compared in terms of their morphology and biological and mechanical behaviors. The morphological results assessed by scanning electron microscopy showed a mes...
Femtosecond laser impact on calcium phosphate bioceramics assessed by micro-Ram...
Lasgorceix, M; Grenho, L; Fernandes, M; Ott, C; Boilet, L; Leriche, A; Monteiro, FJ; Cambier, F; Hocquet, SThe present work is an investigation of the biological response to the presence of grooves 3 µm deep, 15 µm wide and spaced by 100 µm, produced with femtosecond laser on ß-tricalcium phosphate (ß-TCP). The heat affected zone generated by the laser irradiation was investigated. Micro-Raman spectroscopy showed a transformation from ß-TCP phase into a-TCP phase, localised inside the grooves. The X Ray Diffraction ...