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Desafios não atendidos na prevenção da Covid-19 em indivíduos imunocomprometidos

Cunha, Ana Soraia; Raposo, Beatriz; V Cordeiro, João; Marques, Maria João; Pedro, Ana Rita

INTRODUCTION: The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), resulted in significant disease burden and mortality. Despite vaccination successes, new virus variants persist, affecting unvaccinated and immunocompromised individuals (ICI) severely. These high-risk groups face elevated mortality and hospitalization rates. Vigilance and targeted health measures remain...


Efficacy of health literacy interventions aimed to improve health gains of high...

Rosário, Jorge; Raposo, Beatriz; Santos, Eunice; Dias, Sónia; Pedro, Ana Rita

Funding Information: The present publication was funded by Fundação Ciência e Tecnologia, IP national support through CHRC, UIDP/04923/2020. Publisher Copyright: © The Author(s) 2024.; Background: Health literacy (HL) among higher education students is low, making them vulnerable about their health. To reverse this trend, higher education institutions promote HL interventions with various topics and methods. A ...


Management of chronic obstructive pulmonary disease

Cunha, Ana S.; Raposo, Beatriz; Dias, Filipe; Henriques, Susana; Martinho, Hugo; Pedro, Ana R.

Funding Information: This work has been supported by AstraZeneca Produtos Farmacêuticos Lda., a pharmaceutical company with a direct interest in COPD. However, AstraZeneca had no direct role in study design, data collection, and analysis or preparation of the manuscript. AstraZeneca Produtos Farmacêuticos Lda. has approved the decision to publish this work. A.S.C., B.R., F.D., and A.R.P. acknowledge the support...


Portuguese version of the HLS-EU-Q6 and HLS-EU-Q16 questionnaire

Pedro, Ana Rita; Raposo, Beatriz; Luís, Luís; Amaral, Odete; Escoval, Ana; Simões Dias, Sara

Funding Information: The present publication was funded by Fundação Ciência e Tecnologia, IP national support through CHRC, UIDP/04923/2020. Publisher Copyright: © 2023 by the authors.; Health literacy refers to the competencies of individuals and the general population to navigate all the areas of health care, making health decisions. Health professionals need a set of skills and information to adapt to people...


#EntreViagenseAprendizagens

Francisco, Rita; Raposo, Beatriz; Hormigo, Mafalda; Sesifredo, Mónica; Carvalho, Ana; Justo, Ana; Godinho, Cristina albuquerque

Background: Adolescence is a critical period of development in which well-being usually decreases, mental health problems (e.g., depression, anxiety) increase, and lifestyles become less healthy. Schools are a primary setting for the promotion of the well-being and overall health of adolescents, and preventive actions should be a priority within the scope of health-promoting schools. #EntreViagenseAprendizagens...


Interleukin-7 receptor α mutational activation can initiate precursor B-cell ac...

Almeida, Afonso R.M.; Neto, João L.; Cachucho, Ana; Euzébio, Mayara; Meng, Xiangyu; Kim, Rathana; Fernandes, Marta B.; Raposo, Beatriz

Interleukin-7 receptor α (encoded by IL7R) is essential for lymphoid development. Whether acute lymphoblastic leukemia (ALL)-related IL7R gain-of-function mutations can trigger leukemogenesis remains unclear. Here, we demonstrate that lymphoid-restricted mutant IL7R, expressed at physiological levels in conditional knock-in mice, establishes a pre-leukemic stage in which B-cell precursors display self-renewal a...


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