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Tlx3 Exerts Direct Control in Specifying Excitatory Over Inhibitory Neurons in ...
Monteiro, FA; Miranda, RM; Samina, MC; Dias, AF; Raposo, AASF; Oliveira, P; Reguenga, C; Castro, DS; Lima, DThe spinal cord dorsal horn is a major station for integration and relay of somatosensory information and comprises both excitatory and inhibitory neuronal populations. The homeobox gene Tlx3 acts as a selector gene to control the development of late-born excitatory (dILB) neurons by specifying glutamatergic transmitter fate in dorsal spinal cord. However, since Tlx3 direct transcriptional targets remain largel...
Date: 2021
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Origin: Repositório Aberto da Universidade do Porto