25 documents found, page 1 of 3
Analysis of Stereotyped B-Cell Receptor Frequencies Among Portuguese De Novo-Di...
Alves, Daniela; Ferreira, Gisela; Caldas, Joana; Fernandes, Mariana; Gaspar, Cátia; Alpoim, Mafalda; Carvalhais, Inês; Duarte, Sara; Silva, HelenaBackground/objectives: Chronic lymphocytic leukemia (CLL) exhibits a heterogeneous clinical course influenced by genetic factors, such as the mutational status of immunoglobulin variable regions (IGHV). Recently, B-cell receptor (BcR) stereotypes have shown promising prognostic value, potentially surpassing IGHV status. The PAIS study analyzed BcR stereotypes and IGHV mutations in newly diagnosed Portuguese CLL...
Custos e Consequências da Doença Renal Crónica em Pessoas com Diabetes em Portu...
Borges, Margarida; Almeida, Edgar; Alves, Rui; Ascenção, Raquel; Bigotte Vieira, Miguel; Bulhosa, Carolina; Costa, João; S Duarte, Gonçalo; Falcão, LuísIntroduction: Chronic kidney disease is the fastest-growing chronic disease in terms of prevalence and one of the biggest causes of global mortality according to the Global Burden of Disease Collaboration. This study aimed to project the natural disease progression of this disease in people with diabetes, and to quantify the costs and consequences in the Portuguese context. This was achieved by developing an an...
Custos e consequências da doença renal crónica em pessoas com diabetes em Portu...
Borges, Margarida; Almeida, Edgar; Alves, Rui; Ascenção, Raquel; Vieira, Miguel Bigotte; Bulhosa, Carolina; Costa, João; Duarte, Gonçalo S.Introdução: A doença renal crónica é a doença crónica com maior crescimento de prevalência, e uma das maiores causas de mortalidade global de acordo com o Global Burden of Disease Collaboration. O presente estudo teve como objetivo projetar a evolução desta doença em pessoas com diabetes, de modo a quantificar os custos e consequências no contexto português. Tal foi conseguido através do desenvolvimento e param...
Diabetes in the Digital World
Nortadas, Rita; Nascimento do Ó, Dulce; Ribeiro, Rogério; Raposo, JoãoDespite constant pharmacological evolution, diabetes is a particular condition whose control is hard and laborious to achieve. Several aspects contribute to this difficulty. Chronic and acute complications of diabetes represent loss in quality of life and have a significant impact on resource consumption and global health costs. Technological developments have contributed considerably to the paradigm shi...
2023 UPDATE: Luso-Brazilian evidence-based guideline for the management of anti...
Bertoluci, Marcello Casaccia; Júnior, Wellington S. Silva; Valente, Fernando; Araujo, Levimar Rocha; Lyra, Ruy; Castro, João Jácome de; Raposo, JoãoBackground The management of antidiabetic therapy in people with type 2 diabetes (T2D) has evolved beyond gly‑ cemic control. In this context, Brazil and Portugal defned a joint panel of four leading diabetes societies to update the guideline published in 2020. Methods The panelists searched MEDLINE (via PubMed) for the best evidence from clinical studies on treating T2D and its cardiorenal complications. The p...
Effectiveness of exercise training on cancer-related fatigue in colorectal canc...
Machado, Pedro; Morgado, Miguel; Raposo, João; Mendes, Marco; Silva, Cândida G.; Morais, NunoPurpose: To investigate the effects of exercise training on cancer-related fatigue (CRF) in colorectal cancer survivors. Methods: Randomized controlled trials published between 1 January 2010 and 19 October 2020, selected through online search conducted in PubMed, Scopus, Web of Science, SPORTDiscus and PEDro databases, were included. Eligible trials compared the effect of exercise training interventions, versu...
Anomaly detection of consumption in Hotel Units: A case study comparing isolati...
Mendes, Tomás; Cardoso, Pedro; Monteiro, Jânio; Raposo, JoãoBuildings are responsible for a high percentage of global energy consumption, and thus, the improvement of their efficiency can positively impact not only the costs to the companies they house, but also at a global level. One way to reduce that impact is to constantly monitor the consumption levels of these buildings and to quickly act when unjustified levels are detected. Currently, a variety of sensor network...
Avaliação da Problemática da Doença Renal Crónica (Não Diálise) em Portugal: Ab...
Ferreira, Aníbal; Raposo, João; Rocha, João; Polónia, Jorge; Cabrita, José; Jacinto, Nuno; Branco, Patrícia; Birne, Rita; Maia, Margarida; Marcelo, AnaChronic kidney disease is a global public health problem and is associated with an increased risk of serious cardiovascular events and mortality. Since Portugal is one of the European countries with the highest incidence of this pathology, we emphasize the importance of promoting the increase of notoriety of this problem with the health authorities, the health professionals and the scientific community. We pres...
Management of ibrutinib treatment in patients with B-cell malignancies: clinica...
Carda, José Pedro; Santos, Lurdes; Mariz, José Mário; Monteiro, Pedro; Gonçalves, Humberto Miguel; Raposo, João; Silva, Maria Gomes daIbrutinib, a potent inhibitor of the Bruton tyrosine kinase, has revolutionized the treatment of many B-cell malignancies. Ibrutinib has an established favorable toxicity profile with up to 8 years of experience in clinical trials; however, despite ibrutinib's favorable toxicity profile, dose reductions and treatment discontinuations are becoming more evident in clinical practice, particularly in the setting of...
OncoEnergy - Manual de exercício físico para pessoas com cancro
Machado, Pedro; Morgado, Miguel; Raposo, João; Mendes, Marco; Ferreira, Luís Eva; Roque, AnaO presente manual foi desenvolvido por estudantes da Licenciatura em Fisioterapia (Unidade Curricular de Educação e Comunicação em Saúde) e investigadores do Centro de Inovação em Tecnologias e Cuidados de Saúde (ciTechCare) da Escola Superior de Saúde do Instituto Politécnico de Leiria, baseando-se num documento semelhante criado pela Associação Australiana de Ciências do Desporto. A informação apresentada bas...