4 documents found, page 1 of 1
Development, Optimization and Validation of an HPLC-PDA Method for Quantificati...
Almeida,Priscila A. de; Bhering,Carla A. P.; Alves,Michele C.; Oliveira,Marcone A. L. de; Raposo,Nádia R. B.; Ferreira,Anderson O.; Brandão,Marcos A. F.The aqueous extract of the bark of Pinus pinaster has a high concentration of polyphenols represented by a mixture of procyanidins, besides taxifolin, phenolic acids, cinnamic acids and their glycosides. Its quality control is specified in the United States Pharmacopeia, and the assay test is performed by determination of the total procyanidins content. However, determining the individual polyphenol content may...
Synthesis and evaluation of octocrylene-inspired compounds for UV-filter activity
Polonini,Hudson C.; Lopes,Rosângela S.; Beatriz,Adilson; Gomes,Roberto S.; Silva,Adriano O.; Lima,Ricardo V. de; Nunes,Gláucia. A.Octocrylene (2-ethylhexyl 2-cyano-3,3-diphenyl-2-propenoate) is present in several sunscreens and is known to work synergistically with UV filters. We prepared eight octocrylene-related compounds to test their photoprotective activities by measuring diffuse transmittance. The compounds had varied photoprotection profiles, with Sun Protection Factors (SPF) ranging from 1 to 5 and UVA Protection Factors (UVAPF) r...
Transdermal formulations containing human sexual steroids: development and vali...
Polonini,Hudson C.; Soldati,Pedro Paulo; Oliveira,Marcone Augusto Leal de; Brandão,Marcos Antônio F.; Chaves,Maria das Graças M.; Raposo,Nádia R. B.In vitro release of bioidentical hormones in four different liposomal transdermal emulsions (containing testosterone, progesterone, estradiol, or estradiol and estriol) was assessed. For this purpose, novel high-performance liquid chromatography methods were developed and validated in an eco-friendly manner and used to determine the in vitro release of such products. The methods were suitable for our intended g...
Chemical composition and cytotoxicity activity of the essential oil of Pterodon...
Dutra,Rafael C.; Pittella,Frederico; Dittz,Dalton; Marcon,Rodrigo; Pimenta,Daniel S.; Lopes,Miriam T. P.; Raposo,Nádia R. B.Pterodon emarginatus Vogel, Fabaceae, is a native aromatic tree distributed by central region of Brazil. Hydroalcoholic infusions of the seeds are used in folk medicine for their anti-rheumatic and anti-inflammatory properties. The objective of this work was identified the chemical components and verify the cytotoxic effect of the essential oil (EO) from P. emarginatus seeds. Thus, the EO of P. emarginatus seed...