This research was funded by CAPES?PROAP, 2017, Post graduate Program in Surgical Clinics; PQ10/2012?National Council for Scientific and Technological Development (CNPq) grant number: 308995/2012-0.; Universidade de S?o Paulo. Faculdade de Medicina. Department of Surgery. Laboratory of Surgial Physiopathology. S?o Paulo, SP, Brazil.; Universidade de S?o Paulo. Faculdade de Medicina. Department of Emergency Medic...
OBJECTIVES: Intestinal obstruction has a high mortality rate when therapeutic treatment is delayed. Resuscitation in intestinal obstruction requires a large volume of fluid, and fluid combinations have been studied. Therefore, we evaluated the effects of hypertonic saline solution (HS) with pentoxifylline (PTX) on apoptosis, oxidative stress and survival rate. METHODS: Wistar rats were subjected to intestinal o...
OBJECTIVE: To present our experience in the management of patients with infected pancreatic necrosis without drainage. METHODS: The records of patients with pancreatic necrosis admitted to our facility from 2011 to 2015 were retrospectively reviewed. RESULTS: We identified 61 patients with pancreatic necrosis. Six patients with pancreatic necrosis and gas in the retroperitoneum were treated exclusively with cli...